Structure of the human ClC-1 chloride channel

ClC-1 protein channels facilitate rapid passage of chloride ions across cellular membranes, thereby orchestrating skeletal muscle excitability. Malfunction of ClC-1 is associated with myotonia congenita, a disease impairing muscle relaxation. Here, we present the cryo-electron microscopy (cryo-EM) s...

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Detalles Bibliográficos
Autores principales: Wang, Kaituo, Preisler, Sarah Spruce, Zhang, Liying, Cui, Yanxiang, Missel, Julie Winkel, Grønberg, Christina, Gotfryd, Kamil, Lindahl, Erik, Andersson, Magnus, Calloe, Kirstine, Egea, Pascal F., Klaerke, Dan Arne, Pusch, Michael, Pedersen, Per Amstrup, Zhou, Z. Hong, Gourdon, Pontus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6483157/
https://www.ncbi.nlm.nih.gov/pubmed/31022181
http://dx.doi.org/10.1371/journal.pbio.3000218

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