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Competing evolutionary paths in growing populations with applications to multidrug resistance
Investigating the emergence of a particular cell type is a recurring theme in models of growing cellular populations. The evolution of resistance to therapy is a classic example. Common questions are: when does the cell type first occur, and via which sequence of steps is it most likely to emerge? F...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2019
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6483269/ https://www.ncbi.nlm.nih.gov/pubmed/30986219 http://dx.doi.org/10.1371/journal.pcbi.1006866 |