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Functional and biological insights of rCollinein-1, a recombinant serine protease from Crotalus durissus collilineatus

BACKGROUND: The prevalent class of snake venom serine proteases (SVSP) in Viperidae venoms is the thrombin-like enzymes, which, similarly to human thrombin, convert fibrinogen into insoluble fibrin monomers. However, thrombin-like serine proteases differ from thrombin by being unable to activate fac...

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Detalles Bibliográficos
Autores principales: Boldrini-França, Johara, Pinheiro-Junior, Ernesto Lopes, Arantes, Eliane Candiani
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Centro de Estudos de Venenos e Animais Peçonhentos - CEVAP, Universidade Estadual Paulista - UNESP 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6483414/
https://www.ncbi.nlm.nih.gov/pubmed/31131001
http://dx.doi.org/10.1590/1678-9199-JVATITD-1471-18