Cargando…
Genetic variant predictors of gene expression provide new insight into risk of colorectal cancer
Genome-wide association studies have reported 56 independently associated colorectal cancer (CRC) risk variants, most of which are non-coding and believed to exert their effects by modulating gene expression. The computational method PrediXcan uses cis-regulatory variant predictors to impute express...
Ejemplares similares
-
A general framework for functionally informed set-based analysis: Application to a large-scale colorectal cancer study
por: Dong, Xinyuan, et al.
Publicado: (2020) -
Mendelian randomisation study of age at menarche and age at menopause and the risk of colorectal cancer
por: Neumeyer, Sonja, et al.
Publicado: (2018) -
A preliminary investigation of genetic counselors’ information needs when receiving a variant of uncertain significance result: a mixed methods study
por: Scherr, Courtney L., et al.
Publicado: (2015) -
Associations of Height With the Risks of Colorectal and Endometrial Cancer in Persons With Lynch Syndrome
por: Brouwer, Jesca G M, et al.
Publicado: (2020) -
Genetic architectures of proximal and distal colorectal cancer are partly distinct
por: Huyghe, Jeroen R, et al.
Publicado: (2021)