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The metabolic network coherence of human transcriptomes is associated with genetic variation at the cadherin 18 locus
Metabolic coherence (MC) is a network-based approach to dimensionality reduction that can be used, for example, to interpret the joint expression of genes linked to human metabolism. Computationally, the derivation of ‘transcriptomic’ MC involves mapping of an individual gene expression profile onto...
Autores principales: | Schlicht, Kristina, Nyczka, Piotr, Caliebe, Amke, Freitag-Wolf, Sandra, Claringbould, Annique, Franke, Lude, Võsa, Urmo, Kardia, Sharon L. R., Smith, Jennifer A., Zhao, Wei, Gieger, Christian, Peters, Annette, Prokisch, Holger, Strauch, Konstantin, Baurecht, Hansjörg, Weidinger, Stephan, Rosenstiel, Philip, Hütt, Marc-Thorsten, Knecht, Carolin, Szymczak, Silke, Krawczak, Michael |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6483969/ https://www.ncbi.nlm.nih.gov/pubmed/30852652 http://dx.doi.org/10.1007/s00439-019-01994-x |
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