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The metabolic network coherence of human transcriptomes is associated with genetic variation at the cadherin 18 locus

Metabolic coherence (MC) is a network-based approach to dimensionality reduction that can be used, for example, to interpret the joint expression of genes linked to human metabolism. Computationally, the derivation of ‘transcriptomic’ MC involves mapping of an individual gene expression profile onto...

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Detalles Bibliográficos
Autores principales: Schlicht, Kristina, Nyczka, Piotr, Caliebe, Amke, Freitag-Wolf, Sandra, Claringbould, Annique, Franke, Lude, Võsa, Urmo, Kardia, Sharon L. R., Smith, Jennifer A., Zhao, Wei, Gieger, Christian, Peters, Annette, Prokisch, Holger, Strauch, Konstantin, Baurecht, Hansjörg, Weidinger, Stephan, Rosenstiel, Philip, Hütt, Marc-Thorsten, Knecht, Carolin, Szymczak, Silke, Krawczak, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6483969/
https://www.ncbi.nlm.nih.gov/pubmed/30852652
http://dx.doi.org/10.1007/s00439-019-01994-x

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