Cargando…

The PAX6-ZEB2 axis promotes metastasis and cisplatin resistance in non-small cell lung cancer through PI3K/AKT signaling

Paired-box 6 (PAX6) is an important transcription factor required for the function of human neuroectodermal epithelial tissues. Previous studies have suggested that it is also expressed in several types of tumors and has an oncogenic role. However, little is known about its role in non-small cell lu...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wu, Dong-ming, Zhang, Ting, Liu, Ya-bin, Deng, Shi-hua, Han, Rong, Liu, Teng, Li, Jing, Xu, Ying
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6483988/ https://www.ncbi.nlm.nih.gov/pubmed/31024010 http://dx.doi.org/10.1038/s41419-019-1591-4

Ejemplares similares

LncZEB1-AS1 regulates hepatocellular carcinoma bone metastasis via regulation of the miR-302b-EGFR-PI3K-AKT axis
por: Ma, Zhen-jiang, et al.
Publicado: (2020)

Th1 immune maturation effects of Nocardia rubra cell-wall skeleton via PI3K/Akt/PAX8 regulatory axis
por: Zhou, Meixiang, et al.
Publicado: (2022)

SKA3 promotes lung adenocarcinoma metastasis through the EGFR–PI3K–Akt axis
por: Hu, Dan-dan, et al.
Publicado: (2020)

GPX2 promotes EMT and metastasis in non‐small cell lung cancer by activating PI3K/AKT/mTOR/Snail signaling axis
por: Peng, Fang, et al.
Publicado: (2023)

Functional role of MicroRNA/PI3K/AKT axis in osteosarcoma
por: Xiang, Yubo, et al.
Publicado: (2023)

Parthenolide Augments the Chemosensitivity of Non-small-Cell Lung Cancer to Cisplatin via the PI3K/AKT Signaling Pathway
por: Wu, Li-Mei, et al.
Publicado: (2021)

miR-181 regulates cisplatin-resistant non-small cell lung cancer via downregulation of autophagy through the PTEN/PI3K/AKT pathway
por: Liu, Jiangang, et al.
Publicado: (2018)

AFAP1-AS1 induces cisplatin resistance in non-small cell lung cancer through PI3K/AKT pathway
por: Liu, Yang, et al.
Publicado: (2020)

Upregulated hsa_circRNA_100269 inhibits the growth and metastasis of gastric cancer through inactivating PI3K/Akt axis
por: Wang, Zhongli, et al.
Publicado: (2021)

MST4 negatively regulates the EMT, invasion and metastasis of HCC cells by inactivating PI3K/AKT/Snail1 axis
por: Dian, Mei-Juan, et al.
Publicado: (2021)

HOTTIP-miR-205-ZEB2 Axis Confers Cisplatin Resistance to Ovarian Cancer Cells
por: Dong, Yu-Jie, et al.
Publicado: (2021)

Sinomenine sensitizes human gastric cancer cells to cisplatin through negative regulation of PI3K/AKT/Wnt signaling pathway
por: Liu, Ying, et al.
Publicado: (2019)

Cyclooxygenase-2 mediates gefitinib resistance in non-small cell lung cancer through the EGFR/PI3K/AKT axis
por: Deng, Qin-fang, et al.
Publicado: (2020)

Deltonin enhances gastric carcinoma cell apoptosis and chemosensitivity to cisplatin via inhibiting PI3K/AKT/mTOR and MAPK signaling
por: Yang, Lin, et al.
Publicado: (2023)

Cisplatin-Resistant Gastric Cancer Cells Promote the Chemoresistance of Cisplatin-Sensitive Cells via the Exosomal RPS3-Mediated PI3K-Akt-Cofilin-1 Signaling Axis
por: Sun, Meng-Yao, et al.
Publicado: (2021)

Celecoxib enhances anticancer effect of cisplatin and induces anoikis in osteosarcoma via PI3K/Akt pathway
por: Liu, Bing, et al.
Publicado: (2017)

Roles of PI3K/AKT/mTOR Axis in Arteriovenous Fistula
por: Ratti, Stefano, et al.
Publicado: (2022)

Lanthanum Chloride Sensitizes Cisplatin Resistance of Ovarian Cancer Cells via PI3K/Akt Pathway
por: Fang, Shanyu, et al.
Publicado: (2021)

Agmatine Alleviates Cisplatin-Induced Ototoxicity by Activating PI3K/AKT Signaling Pathway
por: Zhang, Ying, et al.
Publicado: (2022)

ABCB5–ZEB1 Axis Promotes Invasion and Metastasis in Breast Cancer Cells
por: Yao, Juntao, et al.
Publicado: (2017)

LINC01296/miR-141-3p/ZEB1-ZEB2 axis promotes tumor metastasis via enhancing epithelial-mesenchymal transition process
por: Sun, Zhenqiang, et al.
Publicado: (2021)

Evodiamine activates cellular apoptosis through suppressing PI3K/AKT and activating MAPK in glioma
por: Wang, Rong, et al.
Publicado: (2018)

ZEB1-AS1/miR-133a-3p/LPAR3/EGFR axis promotes the progression of thyroid cancer by regulating PI3K/AKT/mTOR pathway
por: Xia, Wu, et al.
Publicado: (2020)

Retraction: Parthenolide Augments the Chemosensitivity of Non-small-Cell Lung Cancer to Cisplatin via the PI3K/AKT Signaling Pathway
Publicado: (2021)

Apoptin‐derived peptide reverses cisplatin resistance in gastric cancer through the PI3K–AKT signaling pathway
por: Zhou, Danyang, et al.
Publicado: (2018)

Fangchinoline induces gallbladder cancer cell apoptosis by suppressing PI3K/Akt/XIAP axis
por: Li, Jiandong, et al.
Publicado: (2022)

YBX3 Mediates the Metastasis of Nasopharyngeal Carcinoma via PI3K/AKT Signaling
por: Fan, Xiaoqin, et al.
Publicado: (2021)

Hyperhomocysteinemia potentiates megakaryocyte differentiation and thrombopoiesis via GH-PI3K-Akt axis
por: Lei, Wenjing, et al.
Publicado: (2023)

The PI3K/AKT axis modulates AATF activity in Wilms’ tumor cells
por: Jing, Peng, et al.
Publicado: (2018)

PI3K/AKT signaling pathway as a critical regulator of Cisplatin response in tumor cells
por: NAVAEI, ZAHRA NASRPOUR, et al.
Publicado: (2022)

ZEB1 serves as an oncogene in acute myeloid leukaemia via regulating the PTEN/PI3K/AKT signalling pathway by combining with P53
por: Li, Lanlan, et al.
Publicado: (2021)

Ubiquitin-specific peptidase 17 promotes cisplatin resistance via PI3K/AKT activation in non-small cell lung cancer
por: Zhang, Shengchao, et al.
Publicado: (2020)

Propofol Inhibits Microglial Activation via miR-106b/Pi3k/Akt Axis
por: Liu, Jianhui, et al.
Publicado: (2021)

Zoledronic Acid Enhanced the Antitumor Effect of Cisplatin on Orthotopic Osteosarcoma by ROS-PI3K/AKT Signaling and Attenuated Osteolysis
por: Liu, Liang, et al.
Publicado: (2021)

Reactivation of microRNA-506 inhibits gastric carcinoma cell metastasis through ZEB2
por: Wang, Gui-Jun, et al.
Publicado: (2019)

A PLCB1–PI3K–AKT Signaling Axis Activates EMT to Promote Cholangiocarcinoma Progression
por: Liang, Shuhang, et al.
Publicado: (2021)

Cisplatin regulates cell autophagy in endometrial cancer cells via the PI3K/AKT/mTOR signalling pathway
por: Lin, Qiongyan, et al.
Publicado: (2017)

MicroRNA-758 acts as a tumor inhibitor in colorectal cancer through targeting PAX6 and regulating PI3K/AKT pathway
por: Zhang, Xinli, et al.
Publicado: (2020)

Activation of PI3K/Akt pathway by G protein‐coupled receptor 37 promotes resistance to cisplatin‐induced apoptosis in non‐small cell lung cancer
por: Liu, Han, et al.
Publicado: (2023)

Klotho Sensitizes Human Lung Cancer Cell Line to Cisplatin via PI3k/Akt Pathway
por: Wang, Yan, et al.
Publicado: (2013)

Cannot write session to /tmp/vufind_sessions/sess_o4pj494tedaotap455quqp2809