DMP1 prevents osteocyte alterations, FGF23 elevation and left ventricular hypertrophy in mice with chronic kidney disease

During chronic kidney disease (CKD), alterations in bone and mineral metabolism include increased production of the hormone fibroblast growth factor 23 (FGF23) that may contribute to cardiovascular mortality. The osteocyte protein dentin matrix protein 1 (DMP1) reduces FGF23 and enhances bone minera...

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Detalles Bibliográficos
Autores principales: Dussold, Corey, Gerber, Claire, White, Samantha, Wang, Xueyan, Qi, Lixin, Francis, Connor, Capella, Maralee, Courbon, Guillaume, Wang, Jingya, Li, Chaoyuan, Feng, Jian Q., Isakova, Tamara, Wolf, Myles, David, Valentin, Martin, Aline
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6483996/
https://www.ncbi.nlm.nih.gov/pubmed/31044094
http://dx.doi.org/10.1038/s41413-019-0051-1

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