Cargando…
Vitamin K2 cannot substitute Coenzyme Q(10) as electron carrier in the mitochondrial respiratory chain of mammalian cells
Coenzyme Q(10) (CoQ(10)) deficiencies are a group of heterogeneous conditions that respond to ubiquinone administration if treated soon after the onset of symptoms. However, this treatment is only partially effective due to its poor bioavailability. We tested whether vitamin K2, which was reported t...
Autores principales: | Cerqua, Cristina, Casarin, Alberto, Pierrel, Fabien, Vazquez Fonseca, Luis, Viola, Giampiero, Salviati, Leonardo, Trevisson, Eva |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6484000/ https://www.ncbi.nlm.nih.gov/pubmed/31024065 http://dx.doi.org/10.1038/s41598-019-43014-y |
Ejemplares similares
-
Effect of vanillic acid on COQ6 mutants identified in patients with coenzyme Q(10) deficiency()
por: Doimo, Mara, et al.
Publicado: (2014) -
Impact of Chemical Analogs of 4-Hydroxybenzoic Acid on Coenzyme Q Biosynthesis: From Inhibition to Bypass of Coenzyme Q Deficiency
por: Pierrel, Fabien
Publicado: (2017) -
Molecular characterization of the human COQ5 C-methyltransferase in coenzyme Q(10) biosynthesis()
por: Nguyen, Theresa P.T., et al.
Publicado: (2014) -
Vanillic Acid Restores Coenzyme Q Biosynthesis and ATP Production in Human Cells Lacking COQ6
por: Acosta Lopez, Manuel J., et al.
Publicado: (2019) -
Primary coenzyme Q(10) deficiency presenting as fatal neonatal multiorgan failure
por: Desbats, Maria Andrea, et al.
Publicado: (2015)