Plasma exosomes exacerbate alcohol- and acetaminophen-induced toxicity via CYP2E1 pathway

Cellular CYP2E1 is well-known to mediate alcohol- (ALC) and acetaminophen- (APAP) induced toxicity in hepatic and extra-hepatic cells. Although exosomes have been gaining importance in understanding mechanism of intra- and inter-cellular communication, the functional role of drug metabolizing cytoch...

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Detalles Bibliográficos
Autores principales: Rahman, Mohammad A., Kodidela, Sunitha, Sinha, Namita, Haque, Sanjana, Shukla, Pradeep K., Rao, Radhakrishna, Kumar, Santosh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6484097/
https://www.ncbi.nlm.nih.gov/pubmed/31024054
http://dx.doi.org/10.1038/s41598-019-43064-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6484097/
https://www.ncbi.nlm.nih.gov/pubmed/31024054
http://dx.doi.org/10.1038/s41598-019-43064-2

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