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15-Deoxy-Δ(12,14)-prostaglandin J2 promotes phosphorylation of eukaryotic initiation factor 2α and activates the integrated stress response
Stress granules (SGs) are cytoplasmic RNA–protein aggregates formed in response to inhibition of translation initiation. SGs contribute to the stress response and are implicated in a variety of diseases, including cancer and some forms of neurodegeneration. Neurodegenerative diseases often involve c...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Society for Biochemistry and Molecular Biology
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6484127/ https://www.ncbi.nlm.nih.gov/pubmed/30723157 http://dx.doi.org/10.1074/jbc.RA118.007138 |