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Differential Effects of Unihemispheric Concurrent Dual-Site and Conventional tDCS on Motor Learning: A Randomized, Sham-Controlled Study

INTRODUCTION: Based on the literature, unihemispheric concurrent dual-site anodal transcranial Direct Current Stimulation (a-tDCSUHCDS) of primary Motor cortex (M1) and Dorsolateral Prefrontal Cortex (DLPFC) would be more efficient than conventional a-tDCS of M1 to induce larger and longer-lasting M...

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Autores principales: Talimkhani, Ailin, Abdollahi, Iraj, Mohseni-Bandpei, Mohammad Ali, Ehsani, Fatemeh, Khalili, Sanaz, Jaberzadeh, Shapour
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Iranian Neuroscience Society 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6484181/
https://www.ncbi.nlm.nih.gov/pubmed/31031894
http://dx.doi.org/10.32598/bcn.9.10.350
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author Talimkhani, Ailin
Abdollahi, Iraj
Mohseni-Bandpei, Mohammad Ali
Ehsani, Fatemeh
Khalili, Sanaz
Jaberzadeh, Shapour
author_facet Talimkhani, Ailin
Abdollahi, Iraj
Mohseni-Bandpei, Mohammad Ali
Ehsani, Fatemeh
Khalili, Sanaz
Jaberzadeh, Shapour
author_sort Talimkhani, Ailin
collection PubMed
description INTRODUCTION: Based on the literature, unihemispheric concurrent dual-site anodal transcranial Direct Current Stimulation (a-tDCSUHCDS) of primary Motor cortex (M1) and Dorsolateral Prefrontal Cortex (DLPFC) would be more efficient than conventional a-tDCS of M1 to induce larger and longer-lasting M1 corticospinal excitability. The main objective of the present study was to compare the effects of a-tDCSUHCDS and conventional M1 a-tDCS on the extent and durability of the motor sequence acquisition in healthy individuals. METHODS: In this randomized sham-controlled study, healthy volunteers were randomly divided into three groups: experimental (a-tDCSUHCDS), control (M1 a-tDCS), and sham stimulation groups. The participants practiced serial response time task over three consecutive days when they simultaneously received a-tDCS. Using the skill measure, we assessed motor learning up to 4 weeks after the completion of experimental conditions. RESULTS: Data analysis revealed that all groups exhibited the improved trend over the training course (P<0.001). There were no significant differences in skill acquisition among groups at post-intervention (P>0.05), while a significant improvement was observed between experimental and sham group at the retention time (P<0.05). Moreover, there were no significant differences between the control and two other groups with regard to the retention time (P>0.05). CONCLUSION: These results revealed a significant increase in the skill acquisition by a-tDCSUHCDS technique with regard to retention issue, which could be a valuable finding in neuro-rehabilitation field.
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spelling pubmed-64841812019-04-26 Differential Effects of Unihemispheric Concurrent Dual-Site and Conventional tDCS on Motor Learning: A Randomized, Sham-Controlled Study Talimkhani, Ailin Abdollahi, Iraj Mohseni-Bandpei, Mohammad Ali Ehsani, Fatemeh Khalili, Sanaz Jaberzadeh, Shapour Basic Clin Neurosci Research Paper INTRODUCTION: Based on the literature, unihemispheric concurrent dual-site anodal transcranial Direct Current Stimulation (a-tDCSUHCDS) of primary Motor cortex (M1) and Dorsolateral Prefrontal Cortex (DLPFC) would be more efficient than conventional a-tDCS of M1 to induce larger and longer-lasting M1 corticospinal excitability. The main objective of the present study was to compare the effects of a-tDCSUHCDS and conventional M1 a-tDCS on the extent and durability of the motor sequence acquisition in healthy individuals. METHODS: In this randomized sham-controlled study, healthy volunteers were randomly divided into three groups: experimental (a-tDCSUHCDS), control (M1 a-tDCS), and sham stimulation groups. The participants practiced serial response time task over three consecutive days when they simultaneously received a-tDCS. Using the skill measure, we assessed motor learning up to 4 weeks after the completion of experimental conditions. RESULTS: Data analysis revealed that all groups exhibited the improved trend over the training course (P<0.001). There were no significant differences in skill acquisition among groups at post-intervention (P>0.05), while a significant improvement was observed between experimental and sham group at the retention time (P<0.05). Moreover, there were no significant differences between the control and two other groups with regard to the retention time (P>0.05). CONCLUSION: These results revealed a significant increase in the skill acquisition by a-tDCSUHCDS technique with regard to retention issue, which could be a valuable finding in neuro-rehabilitation field. Iranian Neuroscience Society 2019 2019-01-01 /pmc/articles/PMC6484181/ /pubmed/31031894 http://dx.doi.org/10.32598/bcn.9.10.350 Text en Copyright© 2019 Iranian Neuroscience Society http://creativecommons.org/licenses/by/3.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Paper
Talimkhani, Ailin
Abdollahi, Iraj
Mohseni-Bandpei, Mohammad Ali
Ehsani, Fatemeh
Khalili, Sanaz
Jaberzadeh, Shapour
Differential Effects of Unihemispheric Concurrent Dual-Site and Conventional tDCS on Motor Learning: A Randomized, Sham-Controlled Study
title Differential Effects of Unihemispheric Concurrent Dual-Site and Conventional tDCS on Motor Learning: A Randomized, Sham-Controlled Study
title_full Differential Effects of Unihemispheric Concurrent Dual-Site and Conventional tDCS on Motor Learning: A Randomized, Sham-Controlled Study
title_fullStr Differential Effects of Unihemispheric Concurrent Dual-Site and Conventional tDCS on Motor Learning: A Randomized, Sham-Controlled Study
title_full_unstemmed Differential Effects of Unihemispheric Concurrent Dual-Site and Conventional tDCS on Motor Learning: A Randomized, Sham-Controlled Study
title_short Differential Effects of Unihemispheric Concurrent Dual-Site and Conventional tDCS on Motor Learning: A Randomized, Sham-Controlled Study
title_sort differential effects of unihemispheric concurrent dual-site and conventional tdcs on motor learning: a randomized, sham-controlled study
topic Research Paper
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6484181/
https://www.ncbi.nlm.nih.gov/pubmed/31031894
http://dx.doi.org/10.32598/bcn.9.10.350
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