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Primary teeth microhardness and lead (Pb) levels

OBJECTIVES: Lead (Pb) exposure is associated with dental caries. Whether Pb affects tooth microhardness, is unclear. Our objective was to assess whether Pb concentration is associated with microhardness. METHODS: Exfoliated primary teeth were collected from 46 volunteers. Teeth were sectioned, one h...

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Autores principales: Foxman, Betsy, Kolderman, Ethan, Salzman, Elizabeth, Cronenwett, Anna, Gonzalez-Cabezas, Carlos, Neiswanger, Katherine, Marazita, Mary L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6484203/
https://www.ncbi.nlm.nih.gov/pubmed/31049448
http://dx.doi.org/10.1016/j.heliyon.2019.e01551
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author Foxman, Betsy
Kolderman, Ethan
Salzman, Elizabeth
Cronenwett, Anna
Gonzalez-Cabezas, Carlos
Neiswanger, Katherine
Marazita, Mary L.
author_facet Foxman, Betsy
Kolderman, Ethan
Salzman, Elizabeth
Cronenwett, Anna
Gonzalez-Cabezas, Carlos
Neiswanger, Katherine
Marazita, Mary L.
author_sort Foxman, Betsy
collection PubMed
description OBJECTIVES: Lead (Pb) exposure is associated with dental caries. Whether Pb affects tooth microhardness, is unclear. Our objective was to assess whether Pb concentration is associated with microhardness. METHODS: Exfoliated primary teeth were collected from 46 volunteers. Teeth were sectioned, one half of each tooth was tested for enamel Knoop microhardness. The remaining half was digested and Pb measured using an inductively coupled plasma-mass spectrometer. RESULTS: The correlations between Pb levels and microhardness were very low, and were not statistically significant at p < 0.05. CONCLUSIONS: Previous exposure to high levels of Pb was not associated with decreased tooth microhardness. CLINICAL SIGNIFICANCE: This study assessed whether Pb in deciduous teeth is associated with tooth microhardness. As this was not the case, further studies are needed to identify the mechanisms behind the association between lead exposure and tooth decay.
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spelling pubmed-64842032019-05-02 Primary teeth microhardness and lead (Pb) levels Foxman, Betsy Kolderman, Ethan Salzman, Elizabeth Cronenwett, Anna Gonzalez-Cabezas, Carlos Neiswanger, Katherine Marazita, Mary L. Heliyon Article OBJECTIVES: Lead (Pb) exposure is associated with dental caries. Whether Pb affects tooth microhardness, is unclear. Our objective was to assess whether Pb concentration is associated with microhardness. METHODS: Exfoliated primary teeth were collected from 46 volunteers. Teeth were sectioned, one half of each tooth was tested for enamel Knoop microhardness. The remaining half was digested and Pb measured using an inductively coupled plasma-mass spectrometer. RESULTS: The correlations between Pb levels and microhardness were very low, and were not statistically significant at p < 0.05. CONCLUSIONS: Previous exposure to high levels of Pb was not associated with decreased tooth microhardness. CLINICAL SIGNIFICANCE: This study assessed whether Pb in deciduous teeth is associated with tooth microhardness. As this was not the case, further studies are needed to identify the mechanisms behind the association between lead exposure and tooth decay. Elsevier 2019-04-24 /pmc/articles/PMC6484203/ /pubmed/31049448 http://dx.doi.org/10.1016/j.heliyon.2019.e01551 Text en © 2019 The Authors. Published by Elsevier Ltd. http://creativecommons.org/licenses/by/4.0/ This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Foxman, Betsy
Kolderman, Ethan
Salzman, Elizabeth
Cronenwett, Anna
Gonzalez-Cabezas, Carlos
Neiswanger, Katherine
Marazita, Mary L.
Primary teeth microhardness and lead (Pb) levels
title Primary teeth microhardness and lead (Pb) levels
title_full Primary teeth microhardness and lead (Pb) levels
title_fullStr Primary teeth microhardness and lead (Pb) levels
title_full_unstemmed Primary teeth microhardness and lead (Pb) levels
title_short Primary teeth microhardness and lead (Pb) levels
title_sort primary teeth microhardness and lead (pb) levels
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6484203/
https://www.ncbi.nlm.nih.gov/pubmed/31049448
http://dx.doi.org/10.1016/j.heliyon.2019.e01551
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