A functional interaction between Hippo‐YAP signalling and SREBPs mediates hepatic steatosis in diabetic mice

The Hippo pathway is an evolutionarily conserved regulator of organ size and tumorigenesis that negatively regulates cell growth and survival. Whether the Hippo pathway regulates cell metabolism is unknown. Here, we report that in the nucleus of hepatocytes, Yes‐associated protein(YAP)—the terminal...

Descripción completa

Detalles Bibliográficos
Autores principales: Shu, Zhiping, Gao, Yuan, Zhang, Guopeng, Zhou, Yu, Cao, Jing, Wan, Dongyi, Zhu, Xiaohua, Xiong, Wenqian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6484311/
https://www.ncbi.nlm.nih.gov/pubmed/30821074
http://dx.doi.org/10.1111/jcmm.14262

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6484311/
https://www.ncbi.nlm.nih.gov/pubmed/30821074
http://dx.doi.org/10.1111/jcmm.14262

Ejemplares similares