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ISG12a and its interaction partner NR4A1 are involved in TRAIL‐induced apoptosis in hepatoma cells

Tumor necrosis factor‐related apoptosis‐inducing ligand (TRAIL) can induce apoptosis in cancer cells while sparing normal cells, thereby leading to the development of TRAIL receptor agonists for cancer treatment. However, these agonist‐based therapeutics exhibit little clinical benefits due to the l...

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Detalles Bibliográficos
Autores principales: Liu, Nianli, Wu, Zhiyuan, Chen, Aoxing, Chai, Dafei, Li, Liantao, Zhang, Longzhen, Zheng, Junnian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6484314/
https://www.ncbi.nlm.nih.gov/pubmed/30821058
http://dx.doi.org/10.1111/jcmm.14251