Cargando…

Ligustilide attenuates nitric oxide‐induced apoptosis in rat chondrocytes and cartilage degradation via inhibiting JNK and p38 MAPK pathways

Ligustilide (LIG) is the main lipophilic component of the Umbelliferae family of pharmaceutical plants, including Radix angelicae sinensis and Ligusticum chuanxiong. LIG shows various pharmacological properties associated with anti‐inflammation and anti‐apoptosis in several kinds of cell lines. Howe...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhou, Yan, Ming, Jianghua, Li, Yaming, Deng, Ming, Chen, Qing, Ma, Yonggang, Chen, Zhonghui, Zhang, Yubiao, Liu, Shiqing
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2019
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6484328/ https://www.ncbi.nlm.nih.gov/pubmed/30770640 http://dx.doi.org/10.1111/jcmm.14226

Ejemplares similares

Exosomes derived from miR-126-3p-overexpressing synovial fibroblasts suppress chondrocyte inflammation and cartilage degradation in a rat model of osteoarthritis
por: Zhou, Yan, et al.
Publicado: (2021)

Innate/Inflammatory Bioregulation of Surfactant Protein D Alleviates Rat Osteoarthritis by Inhibiting Toll-Like Receptor 4 Signaling
por: Jiang, Huanyu, et al.
Publicado: (2022)

Neferine induces p38 MAPK/JNK1/2 activation to modulate melanoma proliferation, apoptosis, and oxidative stress
por: Xie, Jun, et al.
Publicado: (2020)

Aciculatin inhibits lipopolysaccharide-mediated inducible nitric oxide synthase and cyclooxygenase-2 expression via suppressing NF-κB and JNK/p38 MAPK activation pathways
por: Hsieh, I-Ni, et al.
Publicado: (2011)

Aprepitant Inhibits JNK and p38/MAPK to Attenuate Inflammation and Suppresses Inflammatory Pain
por: Yang, Yang, et al.
Publicado: (2022)

Functional Roles of JNK and p38 MAPK Signaling in Nasopharyngeal Carcinoma
por: Pua, Lesley Jia Wei, et al.
Publicado: (2022)

A conserved motif in JNK/p38-specific MAPK phosphatases as a determinant for JNK1 recognition and inactivation
por: Liu, Xin, et al.
Publicado: (2016)

Urolithin a attenuates IL-1β-induced inflammatory responses and cartilage degradation via inhibiting the MAPK/NF-κB signaling pathways in rat articular chondrocytes
por: Ding, Sheng-long, et al.
Publicado: (2020)

Antitumor effect of Quercetin on Y79 retinoblastoma cells via activation of JNK and p38 MAPK pathways
por: Liu, Haojie, et al.
Publicado: (2017)

Evaluation of chondrocyte micromass culture for the study of cartilage degradation
por: Morgan, TG, et al.
Publicado: (2005)

miR-520c-3p regulates IL-1β-stimulated human chondrocyte apoptosis and cartilage degradation by targeting GAS2
por: Peng, Le, et al.
Publicado: (2021)

Data on the phosphorylation of p38MAPK and JNK induced by chlorpyrifos in Drosophila melanogaster
por: Batista, J.E.S., et al.
Publicado: (2016)

Octacalcium phosphate crystals directly stimulate expression of inducible nitric oxide synthase through p38 and JNK mitogen-activated protein kinases in articular chondrocytes
por: Ea, Hang-Korng, et al.
Publicado: (2005)

The activation of p38MAPK and JNK pathways in bovine herpesvirus 1 infected MDBK cells
por: Zhu, Liqian, et al.
Publicado: (2016)

Humanin Attenuates NMDA-Induced Excitotoxicity by Inhibiting ROS-dependent JNK/p38 MAPK Pathway
por: Yang, Xiaorong, et al.
Publicado: (2018)

Glabridin Mediate Caspases Activation and Induces Apoptosis through JNK1/2 and p38 MAPK Pathway in Human Promyelocytic Leukemia Cells
por: Huang, Hsin-Lien, et al.
Publicado: (2014)

Tomatidine suppresses inflammation in primary articular chondrocytes and attenuates cartilage degradation in osteoarthritic rats
por: Chu, Xiangyu, et al.
Publicado: (2020)

XMU-MP-1 attenuates osteoarthritis via inhibiting cartilage degradation and chondrocyte apoptosis
por: Hao, Xue, et al.
Publicado: (2022)

Inhibition of cathepsin S confers sensitivity to methyl protodioscin in oral cancer cells via activation of p38 MAPK/JNK signaling pathways
por: Hsieh, Ming-Ju, et al.
Publicado: (2017)

Neurotrophin3 promotes hepatocellular carcinoma apoptosis through the JNK and P38 MAPK pathways
por: Yang, Zhangshuo, et al.
Publicado: (2022)

Ononin ameliorates inflammation and cartilage degradation in rat chondrocytes with IL-1β-induced osteoarthritis by downregulating the MAPK and NF-κB pathways
por: Xu, Fang, et al.
Publicado: (2022)

Correction for: Tomatidine suppresses inflammation in primary articular chondrocytes and attenuates cartilage degradation in osteoarthritic rats
por: Chu, Xiangyu, et al.
Publicado: (2022)

Histone deacetylase-4 and histone deacetylase-8 regulate interleukin-1β-induced cartilage catabolic degradation through MAPK/JNK and ERK pathways
por: Wang, Pengcheng, et al.
Publicado: (2018)

Vicenin 3 ameliorates ECM degradation by regulating the MAPK pathway in SW1353 chondrocytes
por: Chen, Yue-Yuan, et al.
Publicado: (2021)

Coronarin D induces reactive oxygen species-mediated cell death in human nasopharyngeal cancer cells through inhibition of p38 MAPK and activation of JNK
por: Chen, Jui-Chieh, et al.
Publicado: (2017)

Runx2 is required for hypertrophic chondrocyte mediated degradation of cartilage matrix during endochondral ossification
por: Rashid, Harunur, et al.
Publicado: (2021)

Activation of JNK and p38 MAPK Mediated by ZDHHC17 Drives Glioblastoma Multiforme Development and Malignant Progression
por: Chen, Xueran, et al.
Publicado: (2020)

An In Vitro Model of Cartilage Degradation by Chondrocytes in a Three-Dimensional Culture System
por: Nakashima, Katsuhito, et al.
Publicado: (2012)

Bioinformatics and computational chemistry approaches to explore the mechanism of the anti-depressive effect of ligustilide
por: Zhang, Kun, et al.
Publicado: (2023)

CircGLCE alleviates intervertebral disc degeneration by regulating apoptosis and matrix degradation through the targeting of miR-587/STAP1
por: Chen, Zhonghui, et al.
Publicado: (2020)

Nonthermal Plasma Induces Apoptosis in ATC Cells: Involvement of JNK and p38 MAPK-Dependent ROS
por: Lee, Sei Young, et al.
Publicado: (2014)

Bavachinin Induces Oxidative Damage in HepaRG Cells through p38/JNK MAPK Pathways
por: Wang, Shan, et al.
Publicado: (2018)

The Identification of CD163 Expressing Phagocytic Chondrocytes in Joint Cartilage and Its Novel Scavenger Role in Cartilage Degradation
por: Jiao, Kai, et al.
Publicado: (2013)

PKR Promotes Oxidative Stress and Apoptosis of Human Articular Chondrocytes by Causing Mitochondrial Dysfunction through p38 MAPK Activation—PKR Activation Causes Apoptosis in Human Chondrocytes
por: Ma, Ching-Hou, et al.
Publicado: (2019)

Sanmiao formula inhibits chondrocyte apoptosis and cartilage matrix degradation in a rat model of osteoarthritis
por: XU, YING, et al.
Publicado: (2014)

Tissue engineering: chondrocytes and cartilage
por: Hardingham, Tim, et al.
Publicado: (2002)

The role of MAPK11/12/13/14 (p38 MAPK) protein in dopamine agonist-resistant prolactinomas
por: Wang, Shuman, et al.
Publicado: (2021)

Schisandrin A Inhibits the IL-1β-Induced Inflammation and Cartilage Degradation via Suppression of MAPK and NF-κB Signal Pathways in Rat Chondrocytes
por: Tu, Chang, et al.
Publicado: (2019)

Effect of ligustilide on Ang II-induced hypertrophy in cardiomyocytes and the potential mechanisms
por: LU, QUN, et al.
Publicado: (2014)

The Effect of Z-Ligustilide on the Mobility of Human Glioblastoma T98G Cells
por: Yin, Jun, et al.
Publicado: (2013)

Cannot write session to /tmp/vufind_sessions/sess_mikivir499uoedhvvoqp9085vf