TRAF6 directs FOXP3 localization and facilitates regulatory T‐cell function through K63‐linked ubiquitination

Regulatory T cells (Tregs) are crucial mediators of immune control. The characteristic gene expression and suppressive functions of Tregs depend considerably on the stable expression and activity of the transcription factor FOXP3. Transcriptional regulation of the Foxp3 gene has been studied in dept...

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Detalles Bibliográficos
Autores principales: Ni, Xuhao, Kou, Wei, Gu, Jian, Wei, Ping, Wu, Xiao, Peng, Hao, Tao, Jinhui, Yan, Wei, Yang, Xiaoping, Lebid, Andriana, Park, Benjamin V, Chen, Zuojia, Tian, Yizhu, Fu, Juan, Newman, Stephanie, Wang, Xiaoming, Shen, Hongbin, Li, Bin, Blazar, Bruce R., Wang, Xuehao, Barbi, Joseph, Pan, Fan, Lu, Ling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6484404/
https://www.ncbi.nlm.nih.gov/pubmed/30886050
http://dx.doi.org/10.15252/embj.201899766

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