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Intrinsic lipid binding activity of ATG16L1 supports efficient membrane anchoring and autophagy

Membrane targeting of autophagy‐related complexes is an important step that regulates their activities and prevents their aberrant engagement on non‐autophagic membranes. ATG16L1 is a core autophagy protein implicated at distinct phases of autophagosome biogenesis. In this study, we dissected the re...

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Detalles Bibliográficos
Autores principales: Dudley, Leo J, Cabodevilla, Ainara G, Makar, Agata N, Sztacho, Martin, Michelberger, Tim, Marsh, Joseph A, Houston, Douglas R, Martens, Sascha, Jiang, Xuejun, Gammoh, Noor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6484409/
https://www.ncbi.nlm.nih.gov/pubmed/30936093
http://dx.doi.org/10.15252/embj.2018100554