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Intrinsic lipid binding activity of ATG16L1 supports efficient membrane anchoring and autophagy
Membrane targeting of autophagy‐related complexes is an important step that regulates their activities and prevents their aberrant engagement on non‐autophagic membranes. ATG16L1 is a core autophagy protein implicated at distinct phases of autophagosome biogenesis. In this study, we dissected the re...
Autores principales: | Dudley, Leo J, Cabodevilla, Ainara G, Makar, Agata N, Sztacho, Martin, Michelberger, Tim, Marsh, Joseph A, Houston, Douglas R, Martens, Sascha, Jiang, Xuejun, Gammoh, Noor |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6484409/ https://www.ncbi.nlm.nih.gov/pubmed/30936093 http://dx.doi.org/10.15252/embj.2018100554 |
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