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Evaluation of Machine Learning Classifiers to Predict Compound Mechanism of Action When Transferred across Distinct Cell Lines

Multiparametric high-content imaging assays have become established to classify cell phenotypes from functional genomic and small-molecule library screening assays. Several groups have implemented machine learning classifiers to predict the mechanism of action of phenotypic hit compounds by comparin...

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Detalles Bibliográficos
Autores principales:	Warchal, Scott J., Dawson, John C., Carragher, Neil O.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	SAGE Publications 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6484528/ https://www.ncbi.nlm.nih.gov/pubmed/30694704 http://dx.doi.org/10.1177/2472555218820805

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