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Long-term Outcomes of Endovascular and Open Repair for Traumatic Thoracic Aortic Injury
IMPORTANCE: Thoracic endovascular aortic repair (TEVAR) has been adopted rapidly for treating traumatic thoracic aortic injury (TAI). The long-term durability and efficacy remain unknown. OBJECTIVE: To determine the long-term outcomes of thoracic endovascular aortic repair and those of open repair (...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Medical Association
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6484615/ https://www.ncbi.nlm.nih.gov/pubmed/30735232 http://dx.doi.org/10.1001/jamanetworkopen.2018.7861 |
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author | Cheng, Yu-Ting Cheng, Chi-Tung Wang, Shang-Yu Wu, Victor Chien-Chia Chu, Pao-Hsien Chou, An-Hsun Chen, Ching-Chang Ko, Po-Jen Liu, Kuo-Sheng Chen, Shao-Wei |
author_facet | Cheng, Yu-Ting Cheng, Chi-Tung Wang, Shang-Yu Wu, Victor Chien-Chia Chu, Pao-Hsien Chou, An-Hsun Chen, Ching-Chang Ko, Po-Jen Liu, Kuo-Sheng Chen, Shao-Wei |
author_sort | Cheng, Yu-Ting |
collection | PubMed |
description | IMPORTANCE: Thoracic endovascular aortic repair (TEVAR) has been adopted rapidly for treating traumatic thoracic aortic injury (TAI). The long-term durability and efficacy remain unknown. OBJECTIVE: To determine the long-term outcomes of thoracic endovascular aortic repair and those of open repair (OR) for traumatic TAI. DESIGN, SETTING, PARTICIPANTS: This nationwide cohort study used Taiwan’s National Health Insurance Database to evaluate patients with traumatic TAI between January 1, 2004, and December 31, 2013. This single-payer National Health Insurance program covered more than 99.9% of the Taiwanese population. Those who received OR or TEVAR for TAI by propensity score matching were included. Data analysis was conducted in October 2017. EXPOSURES: Thoracic endovascular aortic repair vs open repair. MAIN OUTCOMES AND MEASURES: In-hospital outcomes, all-cause mortality, aorta reintervention, and stroke during follow-up. RESULTS: Of the 287 patients (mean [SD] age, 41.66 [17.98] years; 80.5% male) who received OR or TEVAR for TAI, propensity score matching yielded 100 patients each in the OR and TEVAR groups. After propensity score matching, in-hospital mortality risk was significantly lower in the TEVAR group (9 [9.0%]) than in the OR group (27 [27.0%]; TEVAR vs open repair: odds ratio, 0.27; 95% CI, 0.12-0.60). With a mean (SD) follow-up of 2.80 (2.63) years, the proportion of survivors was 71.9% at 1 year, 70.8% at 2 years, 68.2% at 3 years, and 65.1% at 5 years in the OR group vs 88.9% at 1 year, 88.9% at 2 years, 88.9% at 3 years, and 88.9% at 5 years in the TEVAR group (log-rank test, P < .001). The TEVAR group had only 2 events (2%) of late reintervention and 1 event (1%) of late cerebrovascular accident. The proportion of freedom from reintervention was 100% at 1 year, 100% at 2 years, 100% at 3 years, and 100% at 5 years in the OR group vs 97.4% at 1 year, 97.4% at 2 years, 97.4% at 3 years, and 97.4% at 5 years in the TEVAR group (log-rank test, P = .18). CONCLUSION AND RELEVANCE: Compared with OR, TEVAR was associated with better long-term outcomes, mainly owing to lower mortality during the perioperative period. In addition, TEVAR was associated with a similar rate of survival and reintervention after hospital discharge. |
format | Online Article Text |
id | pubmed-6484615 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
publisher | American Medical Association |
record_format | MEDLINE/PubMed |
spelling | pubmed-64846152019-05-21 Long-term Outcomes of Endovascular and Open Repair for Traumatic Thoracic Aortic Injury Cheng, Yu-Ting Cheng, Chi-Tung Wang, Shang-Yu Wu, Victor Chien-Chia Chu, Pao-Hsien Chou, An-Hsun Chen, Ching-Chang Ko, Po-Jen Liu, Kuo-Sheng Chen, Shao-Wei JAMA Netw Open Original Investigation IMPORTANCE: Thoracic endovascular aortic repair (TEVAR) has been adopted rapidly for treating traumatic thoracic aortic injury (TAI). The long-term durability and efficacy remain unknown. OBJECTIVE: To determine the long-term outcomes of thoracic endovascular aortic repair and those of open repair (OR) for traumatic TAI. DESIGN, SETTING, PARTICIPANTS: This nationwide cohort study used Taiwan’s National Health Insurance Database to evaluate patients with traumatic TAI between January 1, 2004, and December 31, 2013. This single-payer National Health Insurance program covered more than 99.9% of the Taiwanese population. Those who received OR or TEVAR for TAI by propensity score matching were included. Data analysis was conducted in October 2017. EXPOSURES: Thoracic endovascular aortic repair vs open repair. MAIN OUTCOMES AND MEASURES: In-hospital outcomes, all-cause mortality, aorta reintervention, and stroke during follow-up. RESULTS: Of the 287 patients (mean [SD] age, 41.66 [17.98] years; 80.5% male) who received OR or TEVAR for TAI, propensity score matching yielded 100 patients each in the OR and TEVAR groups. After propensity score matching, in-hospital mortality risk was significantly lower in the TEVAR group (9 [9.0%]) than in the OR group (27 [27.0%]; TEVAR vs open repair: odds ratio, 0.27; 95% CI, 0.12-0.60). With a mean (SD) follow-up of 2.80 (2.63) years, the proportion of survivors was 71.9% at 1 year, 70.8% at 2 years, 68.2% at 3 years, and 65.1% at 5 years in the OR group vs 88.9% at 1 year, 88.9% at 2 years, 88.9% at 3 years, and 88.9% at 5 years in the TEVAR group (log-rank test, P < .001). The TEVAR group had only 2 events (2%) of late reintervention and 1 event (1%) of late cerebrovascular accident. The proportion of freedom from reintervention was 100% at 1 year, 100% at 2 years, 100% at 3 years, and 100% at 5 years in the OR group vs 97.4% at 1 year, 97.4% at 2 years, 97.4% at 3 years, and 97.4% at 5 years in the TEVAR group (log-rank test, P = .18). CONCLUSION AND RELEVANCE: Compared with OR, TEVAR was associated with better long-term outcomes, mainly owing to lower mortality during the perioperative period. In addition, TEVAR was associated with a similar rate of survival and reintervention after hospital discharge. American Medical Association 2019-02-08 /pmc/articles/PMC6484615/ /pubmed/30735232 http://dx.doi.org/10.1001/jamanetworkopen.2018.7861 Text en Copyright 2019 Cheng Y-T et al. JAMA Network Open. http://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the terms of the CC-BY License. |
spellingShingle | Original Investigation Cheng, Yu-Ting Cheng, Chi-Tung Wang, Shang-Yu Wu, Victor Chien-Chia Chu, Pao-Hsien Chou, An-Hsun Chen, Ching-Chang Ko, Po-Jen Liu, Kuo-Sheng Chen, Shao-Wei Long-term Outcomes of Endovascular and Open Repair for Traumatic Thoracic Aortic Injury |
title | Long-term Outcomes of Endovascular and Open Repair for Traumatic Thoracic Aortic Injury |
title_full | Long-term Outcomes of Endovascular and Open Repair for Traumatic Thoracic Aortic Injury |
title_fullStr | Long-term Outcomes of Endovascular and Open Repair for Traumatic Thoracic Aortic Injury |
title_full_unstemmed | Long-term Outcomes of Endovascular and Open Repair for Traumatic Thoracic Aortic Injury |
title_short | Long-term Outcomes of Endovascular and Open Repair for Traumatic Thoracic Aortic Injury |
title_sort | long-term outcomes of endovascular and open repair for traumatic thoracic aortic injury |
topic | Original Investigation |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6484615/ https://www.ncbi.nlm.nih.gov/pubmed/30735232 http://dx.doi.org/10.1001/jamanetworkopen.2018.7861 |
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