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Primary Bone Tumors in Children and Adolescents Treated at a Referral Center in Northern Tanzania

Bone tumors account for a small fraction of childhood cancers. Most published reports are from developed countries. The purpose of this study was to review the primary bone tumors in children and adolescents treated at a referral center in Northern Tanzania. We completed a 10-year hospital-based cro...

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Autores principales: Ghert, Michelle, Mwita, Winfrida, Mandari, Faiton Ndesanjo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6484668/
https://www.ncbi.nlm.nih.gov/pubmed/31157317
http://dx.doi.org/10.5435/JAAOSGlobal-D-17-00045
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author Ghert, Michelle
Mwita, Winfrida
Mandari, Faiton Ndesanjo
author_facet Ghert, Michelle
Mwita, Winfrida
Mandari, Faiton Ndesanjo
author_sort Ghert, Michelle
collection PubMed
description Bone tumors account for a small fraction of childhood cancers. Most published reports are from developed countries. The purpose of this study was to review the primary bone tumors in children and adolescents treated at a referral center in Northern Tanzania. We completed a 10-year hospital-based cross-sectional study in which all patients younger than 20 years diagnosed with a primary bone tumor at the Kilimanjaro Christian Medical Center Orthopaedic Department from January 2006 to December 2015 were identified and reviewed. Of the 80 identified patients, 15 (18.8%) were aged 5 to 8 years, and 65 (81%) were aged 9 to 19 years. Forty-seven males (59%) and 33 females (41%) were identified. The most common tumor locations were the femur, tibia, and humerus. Osteosarcoma was the most common malignant diagnosis (49 patients, 61%). No cases of Ewing sarcoma were reported. The most common tribal origins of the patients were Chagga and Maasai. Most primary bone tumors treated at a referral center in Northern Tanzania are malignant, with osteosarcoma representing the vast majority. No cases of Ewing sarcoma were identified in this tertiary referral hospital–based database.
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spelling pubmed-64846682019-05-29 Primary Bone Tumors in Children and Adolescents Treated at a Referral Center in Northern Tanzania Ghert, Michelle Mwita, Winfrida Mandari, Faiton Ndesanjo J Am Acad Orthop Surg Glob Res Rev Research Article Bone tumors account for a small fraction of childhood cancers. Most published reports are from developed countries. The purpose of this study was to review the primary bone tumors in children and adolescents treated at a referral center in Northern Tanzania. We completed a 10-year hospital-based cross-sectional study in which all patients younger than 20 years diagnosed with a primary bone tumor at the Kilimanjaro Christian Medical Center Orthopaedic Department from January 2006 to December 2015 were identified and reviewed. Of the 80 identified patients, 15 (18.8%) were aged 5 to 8 years, and 65 (81%) were aged 9 to 19 years. Forty-seven males (59%) and 33 females (41%) were identified. The most common tumor locations were the femur, tibia, and humerus. Osteosarcoma was the most common malignant diagnosis (49 patients, 61%). No cases of Ewing sarcoma were reported. The most common tribal origins of the patients were Chagga and Maasai. Most primary bone tumors treated at a referral center in Northern Tanzania are malignant, with osteosarcoma representing the vast majority. No cases of Ewing sarcoma were identified in this tertiary referral hospital–based database. Wolters Kluwer 2019-03-05 /pmc/articles/PMC6484668/ /pubmed/31157317 http://dx.doi.org/10.5435/JAAOSGlobal-D-17-00045 Text en Copyright © 2019 The Authors. Published by Wolters Kluwer Health, Inc. on behalf of the American Academy of Orthopaedic Surgeons. This is an open access article distributed under the Creative Commons Attribution License 4.0 (CCBY) (http://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Ghert, Michelle
Mwita, Winfrida
Mandari, Faiton Ndesanjo
Primary Bone Tumors in Children and Adolescents Treated at a Referral Center in Northern Tanzania
title Primary Bone Tumors in Children and Adolescents Treated at a Referral Center in Northern Tanzania
title_full Primary Bone Tumors in Children and Adolescents Treated at a Referral Center in Northern Tanzania
title_fullStr Primary Bone Tumors in Children and Adolescents Treated at a Referral Center in Northern Tanzania
title_full_unstemmed Primary Bone Tumors in Children and Adolescents Treated at a Referral Center in Northern Tanzania
title_short Primary Bone Tumors in Children and Adolescents Treated at a Referral Center in Northern Tanzania
title_sort primary bone tumors in children and adolescents treated at a referral center in northern tanzania
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6484668/
https://www.ncbi.nlm.nih.gov/pubmed/31157317
http://dx.doi.org/10.5435/JAAOSGlobal-D-17-00045
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