Mitochondrial dysfunction is a key determinant of the rare disease lymphangioleiomyomatosis and provides a novel therapeutic target

Lymphangioleiomyomatosis (LAM) is a rare and progressive systemic disease affecting mainly young women of childbearing age. A deterioration in lung function is driven by neoplastic growth of atypical smooth muscle-like LAM cells in the pulmonary interstitial space that leads to cystic lung destructi...

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Detalles Bibliográficos
Autores principales: Abdelwahab, E. M. M., Pal, S., Kvell, K., Sarosi, V., Bai, P., Rue, R., Krymskaya, V., McPhail, D., Porter, A., Pongracz, J. E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Brief Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6484686/
https://www.ncbi.nlm.nih.gov/pubmed/30573768
http://dx.doi.org/10.1038/s41388-018-0625-1

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