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DNA-binding mechanism of spiropyran photoswitches: the role of electrostatics
The binding mechanism of the protonated open form of three spiropyran derivatives into a 12-mer (poly-dAT)(2) has been unveiled by means of computational methods. It is found that the electrostatic term in the probe:DNA binding energy, modulates the binding mode, providing new guidelines for the des...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Royal Society of Chemistry
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6484825/ https://www.ncbi.nlm.nih.gov/pubmed/30801589 http://dx.doi.org/10.1039/c8cp07508e |