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Expression Characteristics of Genes Hypermethylated and Downregulated in Rat Liver Specific to Nongenotoxic Hepatocarcinogens

This study examined hypermethylated and downregulated genes specific to carbon tetrachloride (CCl(4)) by Methyl-Seq analysis combined with expression microarray analysis in the liver of rats treated with CCl(4) or N-nitrosodiethylamine (DEN) for 28 days, by excluding those with DEN. Among 52 genes,...

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Detalles Bibliográficos
Autores principales:	Ito, Yuko, Nakajima, Kota, Masubuchi, Yasunori, Kikuchi, Satomi, Saito, Fumiyo, Akahori, Yumi, Jin, Meilan, Yoshida, Toshinori, Shibutani, Makoto
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2019
Materias:	Evaluation of Genes Involved in Non-Genotoxic Carcinogenesis
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6484883/ https://www.ncbi.nlm.nih.gov/pubmed/30690589 http://dx.doi.org/10.1093/toxsci/kfz027

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