Meprin β metalloproteases associated with differential metabolite profiles in the plasma and urine of mice with type 1 diabetes and diabetic nephropathy

BACKGROUND: Meprin metalloproteases are abundantly expressed in the brush border membranes of kidney proximal tubules and small intestines. Meprins are also expressed in podocytes and leukocytes (monocytes and macrophages). Meprins are implicated in the pathophysiology of diabetic nephropathy (DN) b...

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Detalles Bibliográficos
Autores principales: Gooding, Jessica, Cao, Lei, Whitaker, Courtney, Mwiza, Jean-Marie, Fernander, Mizpha, Ahmed, Faihaa, Acuff, Zach, McRitchie, Susan, Sumner, Susan, Ongeri, Elimelda Moige
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6485094/
https://www.ncbi.nlm.nih.gov/pubmed/31023251
http://dx.doi.org/10.1186/s12882-019-1313-2

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