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Transcriptome analysis of normal-appearing white matter reveals cortisol- and disease-associated gene expression profiles in multiple sclerosis

Inter-individual differences in cortisol production by the hypothalamus–pituitary–adrenal (HPA) axis are thought to contribute to clinical and pathological heterogeneity of multiple sclerosis (MS). At the same time, accumulating evidence indicates that MS pathogenesis may originate in the normal-app...

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Detalles Bibliográficos
Autores principales: Melief, Jeroen, Orre, Marie, Bossers, Koen, van Eden, Corbert G., Schuurman, Karianne G., Mason, Matthew R. J., Verhaagen, Joost, Hamann, Jörg, Huitinga, Inge
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6485096/
https://www.ncbi.nlm.nih.gov/pubmed/31023360
http://dx.doi.org/10.1186/s40478-019-0705-7