A Novel TNF-α-Targeting Aptamer for TNF-α-Mediated Acute Lung Injury and Acute Liver Failure

Rationale: The TNF-α pathway plays as a double-edged sword that simultaneously regulates cell apoptosis and proliferation. The dysregulated TNF-α signaling can trigger cytokine storms that lead to profound cell death during the phase of acute tissue injury. On the other hand, an optimal level of TNF...

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Detalles Bibliográficos
Autores principales: Lai, Wei-Yun, Wang, Jen-Wei, Huang, Bo-Tsang, Lin, Emily Pei-Ying, Yang, Pan-Chyr
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2019
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6485186/
https://www.ncbi.nlm.nih.gov/pubmed/31037135
http://dx.doi.org/10.7150/thno.30972

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