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Molecular Imaging of Immune Cell Dynamics During De- and Remyelination in the Cuprizone Model of Multiple Sclerosis by [(18)F]DPA-714 PET and MRI
Background: Activation and dysregulation of innate, adaptive and resident immune cells in response to damage determine the pathophysiology of demyelinating disorders. Among the plethora of involved cells, microglia/macrophages and astrocytes play an important role in the pathogenesis of demyelinatin...
Autores principales: | Zinnhardt, Bastian, Belloy, Michaël, Fricke, Inga B., Orije, Jasmien, Guglielmetti, Caroline, Hermann, Sven, Wagner, Stefan, Schäfers, Michael, Van der Linden, Annemie, Jacobs, Andreas H. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Ivyspring International Publisher
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6485187/ https://www.ncbi.nlm.nih.gov/pubmed/31037121 http://dx.doi.org/10.7150/thno.32461 |
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