CYP2C11 played a significant role in down-regulating rat blood pressure under the challenge of a high-salt diet

BACKGROUND: Arachidonic acid (AA) is oxidized by cytochrome P450s (CYPs) to form epoxyeicosatrienoic acids (EETs), compounds that modulate ion transport, gene expression, and vasorelaxation. Both CYP2Cs and CYP2Js are involved in kidney EET epoxidation. METHODS: In this study, we used a CYP2C11-null...

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Detalles Bibliográficos
Autores principales: Liu, Wei, Sui, Danjuan, Ye, Huanying, Ouyang, Zhen, Wei, Yuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PeerJ Inc. 2019
Materias:
Biochemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6485204/
https://www.ncbi.nlm.nih.gov/pubmed/31065462
http://dx.doi.org/10.7717/peerj.6807

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6485204/
https://www.ncbi.nlm.nih.gov/pubmed/31065462
http://dx.doi.org/10.7717/peerj.6807

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