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CYP2C11 played a significant role in down-regulating rat blood pressure under the challenge of a high-salt diet
BACKGROUND: Arachidonic acid (AA) is oxidized by cytochrome P450s (CYPs) to form epoxyeicosatrienoic acids (EETs), compounds that modulate ion transport, gene expression, and vasorelaxation. Both CYP2Cs and CYP2Js are involved in kidney EET epoxidation. METHODS: In this study, we used a CYP2C11-null...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
PeerJ Inc.
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6485204/ https://www.ncbi.nlm.nih.gov/pubmed/31065462 http://dx.doi.org/10.7717/peerj.6807 |