Non-invasive diagnosis of early-stage lung cancer using high-throughput targeted DNA methylation sequencing of circulating tumor DNA (ctDNA)

Rational: LDCT screening can identify early-stage lung cancers yet introduces excessive false positives and it remains a great challenge to differentiate malignant tumors from benign solitary pulmonary nodules, which calls for better non-invasive diagnostic tools. Methods: We performed DNA methylati...

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Detalles Bibliográficos
Autores principales: Liang, Wenhua, Zhao, Yue, Huang, Weizhe, Gao, Yangbin, Xu, Weihong, Tao, Jinsheng, Yang, Meng, Li, Lequn, Ping, Wei, Shen, Hui, Fu, Xiangning, Chen, Zhiwei, Laird, Peter W., Cai, Xuyu, Fan, Jian-Bing, He, Jianxing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2019
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6485294/
https://www.ncbi.nlm.nih.gov/pubmed/31037156
http://dx.doi.org/10.7150/thno.28119

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