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Enhanced Performance of Next-Generation Sequencing Diagnostics Compared With Standard of Care Microbiological Diagnostics in Patients Suffering From Septic Shock

OBJECTIVES: Culture-based diagnostics represent the standard of care in septic patients, but are highly insensitive and in many cases unspecific. We recently demonstrated the general feasibility of next-generation sequencing-based diagnostics using free circulating nucleic acids (cell-free DNA) in p...

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Detalles Bibliográficos
Autores principales: Grumaz, Silke, Grumaz, Christian, Vainshtein, Yevhen, Stevens, Philip, Glanz, Karolina, Decker, Sebastian O., Hofer, Stefan, Weigand, Markus A., Brenner, Thorsten, Sohn, Kai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6485303/
https://www.ncbi.nlm.nih.gov/pubmed/30720537
http://dx.doi.org/10.1097/CCM.0000000000003658