Prediction of acute myeloid leukaemia risk in healthy individuals

The incidence of acute myeloid leukaemia (AML) increases with age and mortality exceeds 90% when diagnosed after age 65. Most cases arise without a detectable prodrome and present with the acute complications of bone marrow failure1. The onset of such de novo AML cases is typically preceded by the a...

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Detalles Bibliográficos
Autores principales: Abelson, Sagi, Collord, Grace, Ng, Stanley W.K., Weissbrod, Omer, Cohen, Netta Mendelson, Niemeyer, Elisabeth, Barda, Noam, Zuzarte, Philip C., Heisler, Lawrence, Sundaravadanam, Yogi, Luben, Robert, Hayat, Shabina, Wang, Ting Ting, Zhao, Zhen, Cirlan, Iulia, Pugh, Trevor J., Soave, David, Ng, Karen, Latimer, Calli, Hardy, Claire, Raine, Keiran, Jones, David, Hoult, Diana, Britten, Abigail, McPherson, John D., Johansson, Mattias, Mbabaali, Faridah, Eagles, Jenna, Miller, Jessica, Pasternack, Danielle, Timms, Lee, Krzyzanowski, Paul, Awadalla, Phillip, Costa, Rui, Segal, Eran, Bratman, Scott V., Beer, Philip, Behjati, Sam, Martincorena, Inigo, Wang, Jean C.Y., Bowles, Kristian M., Quirós, J Ramón, Karakatsani, Anna, La Vecchia, Carlo, Trichopoulou, Antonia, Salamanca-Fernández, Elena, Huerta, José M., Barricarte, Aurelio, Travis, Ruth C., Tumino, Rosario, Masala, Giovanna, Boeing, Heiner, Panico, Salvatore, Kaaks, Rudolf, Krämer, Alwin, Sieri, Sabina, Riboli, Elio, Vineis, Paolo, Foll, Matthieu, McKay, James, Polidoro, Silvia, Sala, Núria, Khaw, Kay-Tee, Vermeulen, Roel, Campbell, Peter J, Papaemmanuil, Elli, Minden, Mark D, Tanay, Amos, Balicer, Ran D, Wareham, Nicholas J, Gerstung, Moritz, Dick, John E., Brennan, Paul, Vassiliou, George S., Shlush, Liran I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6485381/
https://www.ncbi.nlm.nih.gov/pubmed/29988082
http://dx.doi.org/10.1038/s41586-018-0317-6

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