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SumHer better estimates the SNP heritability of complex traits from summary statistics

We present SumHer, software for estimating confounding bias, SNP heritability, enrichments of heritability and genetic correlations using summary statistics from genome-wide association studies. The key difference between SumHer and the existing software LD Score Regression (LDSC) is that SumHer all...

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Detalles Bibliográficos
Autores principales: Speed, Doug, Balding, David J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6485398/
https://www.ncbi.nlm.nih.gov/pubmed/30510236
http://dx.doi.org/10.1038/s41588-018-0279-5