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Blood flow drives lumen formation by inverse membrane blebbing during angiogenesis in vivo

How vascular tubes build, maintain and adapt continuously perfused lumens to meet local metabolic needs remains poorly understood. Recent studies showed that blood flow itself plays a critical role in the remodelling of vascular networks(1,2), and suggested it is also required for lumenisation of ne...

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Detalles Bibliográficos
Autores principales: Gebala, Véronique, Collins, Russell, Geudens, Ilse, Phng, Li-Kun, Gerhardt, Holger
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6485462/
https://www.ncbi.nlm.nih.gov/pubmed/26928868
http://dx.doi.org/10.1038/ncb3320