Cargando…

Low copy number of the salivary amylase gene predisposes to obesity

Detalles Bibliográficos
Autores principales:	Falchi, Mario, Moustafa, Julia Sarah El-Sayed, Takousis, Petros, Pesce, Francesco, Bonnefond, Amélie, Andersson-Assarsson, Johanna C., Sudmant, Peter H., Dorajoo, Rajkumar, Al-Shafai, Mashael Nedham, Bottolo, Leonardo, Ozdemir, Erdal, So, Hon-Cheong, Davies, Robert W., Patrice, Alexandre, Dent, Robert, Mangino, Massimo, Hysi, Pirro G., Dechaume, Aurélie, Huyvaert, Marlène, Skinner, Jane, Pigeyre, Marie, Caiazzo, Robert, Raverdy, Violeta, Vaillant, Emmanuel, Field, Sarah, Balkau, Beverley, Marre, Michel, Visvikis-Siest, Sophie, Weill, Jacques, Poulain-Godefroy, Odile, Jacobson, Peter, Sjostrom, Lars, Hammond, Christopher J., Deloukas, Panos, Sham, Pak Chung, McPherson, Ruth, Lee, Jeannette, Tai, E. Shyong, Sladek, Robert, Carlsson, Lena M.S., Walley, Andrew, Eichler, Evan E., Pattou, Francois, Spector, Timothy D., Froguel, Philippe
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2014
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6485469/ https://www.ncbi.nlm.nih.gov/pubmed/24686848 http://dx.doi.org/10.1038/ng.2939

Ejemplares similares

Relationship between salivary/pancreatic amylase and body mass index: a systems biology approach
por: Bonnefond, Amélie, et al.
Publicado: (2017)

Post-Bariatric Surgery Changes in Quinolinic and Xanthurenic Acid Concentrations Are Associated with Glucose Homeostasis
por: Favennec, Marie, et al.
Publicado: (2016)

Letter to the editor: Regression of liver fibrosis after bariatric operations: A glass two‐third full rather than half empty
por: Pattou, François, et al.
Publicado: (2022)

The Common P446L Polymorphism in GCKR Inversely Modulates Fasting Glucose and Triglyceride Levels and Reduces Type 2 Diabetes Risk in the DESIR Prospective General French Population
por: Vaxillaire, Martine, et al.
Publicado: (2008)

What Is the Contribution of Two Genetic Variants Regulating VEGF Levels to Type 2 Diabetes Risk and to Microvascular Complications?
por: Bonnefond, Amélie, et al.
Publicado: (2013)

Whole-Exome Sequencing and High Throughput Genotyping Identified KCNJ11 as the Thirteenth MODY Gene
por: Bonnefond, Amélie, et al.
Publicado: (2012)

The expression of genes in top obesity-associated loci is enriched in insula and substantia nigra brain regions involved in addiction and reward
por: Ndiaye, Fatou K, et al.
Publicado: (2019)

Analysis of common PTPN1 gene variants in type 2 diabetes, obesity and associated phenotypes in the French population
por: Cheyssac, Claire, et al.
Publicado: (2006)

Analysis of KLF transcription factor family gene variants in type 2 diabetes
por: Gutiérrez-Aguilar, Ruth, et al.
Publicado: (2007)

Loss-of-function mutations in MRAP2 are pathogenic in hyperphagic obesity with hyperglycemia and hypertension
por: Baron, Morgane, et al.
Publicado: (2019)

Preclinical Assessment of Leptin Transport into the Cerebrospinal Fluid in Diet‐Induced Obese Minipigs
por: Chmielewski, Alexandra, et al.
Publicado: (2019)

Impact of statistical models on the prediction of type 2 diabetes using non-targeted metabolomics profiling
por: Yengo, Loic, et al.
Publicado: (2016)

A Genome-Wide Association Study Identifies rs2000999 as a Strong Genetic Determinant of Circulating Haptoglobin Levels
por: Froguel, Philippe, et al.
Publicado: (2012)

Low-Frequency Variants in HMGA1 Are Not Associated With Type 2 Diabetes Risk
por: Marquez, Marcel, et al.
Publicado: (2012)

Impaired histone deacetylases 5 and 6 expression mimics the effects of obesity and hypoxia on adipocyte function
por: Bricambert, Julien, et al.
Publicado: (2016)

Childhood Obesity Is Associated with Shorter Leukocyte Telomere Length
por: Buxton, Jessica L., et al.
Publicado: (2011)

Peroxisomal β-oxidation acts as a sensor for intracellular fatty acids and regulates lipolysis
por: Ding, Lianggong, et al.
Publicado: (2021)

Expression and functional assessment of candidate type 2 diabetes susceptibility genes identify four new genes contributing to human insulin secretion
por: Ndiaye, Fatou K., et al.
Publicado: (2017)

Prevalence of Loss-of-Function FTO Mutations in Lean and Obese Individuals
por: Meyre, David, et al.
Publicado: (2010)

Alcohol Consumption, Beverage Preference, and Diet in Middle-Aged Men from the STANISLAS Study
por: Herbeth, Bernard, et al.
Publicado: (2012)

Inflammatory Role of Toll-Like Receptors in Human and Murine Adipose Tissue
por: Poulain-Godefroy, Odile, et al.
Publicado: (2010)

Evaluating the association of common PBX1 variants with type 2 diabetes
por: Duesing, Konsta, et al.
Publicado: (2008)

Evaluating the association of common APOA2 variants with type 2 diabetes
por: Duesing, Konsta, et al.
Publicado: (2009)

Genetic Variant in HK1 Is Associated With a Proanemic State and A1C but Not Other Glycemic Control–Related Traits
por: Bonnefond, Amélie, et al.
Publicado: (2009)

Evaluation of the Association of IGF2BP2 Variants With Type 2 Diabetes in French Caucasians
por: Duesing, Konsta, et al.
Publicado: (2008)

Next-generation sequencing for identifying new genes in rare genetic diseases: many challenges and a pinch of luck
por: Bonnefond, Amélie, et al.
Publicado: (2013)

Personalised Medicine: The Odyssey from Hope to Practice
por: Visvikis-Siest, Sophie, et al.
Publicado: (2018)

What Is the Best NGS Enrichment Method for the Molecular Diagnosis of Monogenic Diabetes and Obesity?
por: Philippe, Julien, et al.
Publicado: (2015)

The genetic susceptibility to type 2 diabetes may be modulated by obesity status: implications for association studies
por: Cauchi, Stéphane, et al.
Publicado: (2008)

Epigenome-Wide Association Study (EWAS) of Blood Lipids in Healthy Population from STANISLAS Family Study (SFS)
por: Xie, Ting, et al.
Publicado: (2019)

Epigenome-wide association study detects a novel loci associated with central obesity in healthy subjects
por: Xie, Ting, et al.
Publicado: (2021)

Epistatic study reveals two genetic interactions in blood pressure regulation
por: Ndiaye, Ndeye Coumba, et al.
Publicado: (2013)

Heterozygous Mutations Causing Partial Prohormone Convertase 1 Deficiency Contribute to Human Obesity
por: Creemers, John W.M., et al.
Publicado: (2012)

Disruption of a Novel Krüppel-like Transcription Factor p300-regulated Pathway for Insulin Biosynthesis Revealed by Studies of the c.-331 INS Mutation Found in Neonatal Diabetes Mellitus
por: Bonnefond, Amélie, et al.
Publicado: (2011)

Hepatic transcriptomic signatures of statin treatment are associated with impaired glucose homeostasis in severely obese patients
por: Margerie, Daniel, et al.
Publicado: (2019)

Editorial: The path towards precision health: Prospects and challenges
por: Ibrahim, Muntaser E., et al.
Publicado: (2022)

Genetic and Functional Assessment of the Role of the rs13431652-A and rs573225-A Alleles in the G6PC2 Promoter That Are Strongly Associated With Elevated Fasting Glucose Levels
por: Bouatia-Naji, Nabila, et al.
Publicado: (2010)

Post Genome-Wide Association Studies of Novel Genes Associated with Type 2 Diabetes Show Gene-Gene Interaction and High Predictive Value
por: Cauchi, Stéphane, et al.
Publicado: (2008)

Erratum. Ten-Year Outcome of Islet Alone or Islet After Kidney Transplantation in Type 1 Diabetes: A Prospective Parallel-Arm Cohort Study. Diabetes Care 2019;42:2042–2049
por: Vantyghem, Marie-Christine, et al.
Publicado: (2020)

NASH-related increases in plasma bile acid levels depend on insulin resistance
por: Grzych, Guillaume, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_dv7104ohl21fhu2o5qh38tkp8o