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Photo-cross-linking and high-resolution mass spectrometry for assignment of RNA-binding sites in RNA-binding proteins
RNA–protein complexes play pivotal roles in many central biological processes. While methods based on next-generation sequencing have profoundly advanced our ability to identify the specific RNAs bound by a particular protein, there is a dire need for precise and systematic ways to identify RNA inte...
Autores principales: | Kramer, Katharina, Sachsenberg, Timo, Beckmann, Benedikt M., Qamar, Saadia, Boon, Kum-Loong, Hentze, Matthias W., Kohlbacher, Oliver, Urlaub, Henning |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6485471/ https://www.ncbi.nlm.nih.gov/pubmed/25173706 http://dx.doi.org/10.1038/nmeth.3092 |
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