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Serine starvation induces stress and p53 dependent metabolic remodeling in cancer cells

Cancer cells acquire distinct metabolic adaptations to survive stress associated with tumour growth and to satisfy the anabolic demands of proliferation. The tumour suppressor protein p53 influences a range of cellular metabolic processes, including glycolysis(1,2) oxidative phosphorylation(3) (OXPH...

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Detalles Bibliográficos
Autores principales:	Maddocks, Oliver D. K., Berkers, Celia R., Mason, Susan M., Zheng, Liang, Blyth, Karen, Gottlieb, Eyal, Vousden, Karen H.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2012
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6485472/ https://www.ncbi.nlm.nih.gov/pubmed/23242140 http://dx.doi.org/10.1038/nature11743

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