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A Case of Anti-glomerular Basement Disease Without Pulmonary Involvement

Anti-glomerular basement membrane disease is a rare but classic example of an antibody-mediated disease. The scale of injury that it entails depends on the site where the antibodies are deposited, with some patients presenting with a composite of pulmonary and renal damage. In other scenarios, the r...

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Autores principales: Nasrullah, Adeel, Fatima, Zainab, Javed, Anam, Tariq, Usman, Saleem, Muhammad Sabih
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6485522/
https://www.ncbi.nlm.nih.gov/pubmed/31058013
http://dx.doi.org/10.7759/cureus.4130
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author Nasrullah, Adeel
Fatima, Zainab
Javed, Anam
Tariq, Usman
Saleem, Muhammad Sabih
author_facet Nasrullah, Adeel
Fatima, Zainab
Javed, Anam
Tariq, Usman
Saleem, Muhammad Sabih
author_sort Nasrullah, Adeel
collection PubMed
description Anti-glomerular basement membrane disease is a rare but classic example of an antibody-mediated disease. The scale of injury that it entails depends on the site where the antibodies are deposited, with some patients presenting with a composite of pulmonary and renal damage. In other scenarios, the renal system is the main site of affliction with patients deteriorating to a status of acute renal failure within days of diagnosis. Due to the paucity of its incidence, we present our findings of anti-glomerular basement disease with pulmonary sparing. Herein, we also review the array of different physical findings, different forms of perpetrating antibodies, the diagnostic tools at our disposal, and the treatment modalities utilized to prevent catastrophic tissue injuries. 
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spelling pubmed-64855222019-05-03 A Case of Anti-glomerular Basement Disease Without Pulmonary Involvement Nasrullah, Adeel Fatima, Zainab Javed, Anam Tariq, Usman Saleem, Muhammad Sabih Cureus Internal Medicine Anti-glomerular basement membrane disease is a rare but classic example of an antibody-mediated disease. The scale of injury that it entails depends on the site where the antibodies are deposited, with some patients presenting with a composite of pulmonary and renal damage. In other scenarios, the renal system is the main site of affliction with patients deteriorating to a status of acute renal failure within days of diagnosis. Due to the paucity of its incidence, we present our findings of anti-glomerular basement disease with pulmonary sparing. Herein, we also review the array of different physical findings, different forms of perpetrating antibodies, the diagnostic tools at our disposal, and the treatment modalities utilized to prevent catastrophic tissue injuries.  Cureus 2019-02-25 /pmc/articles/PMC6485522/ /pubmed/31058013 http://dx.doi.org/10.7759/cureus.4130 Text en Copyright © 2019, Nasrullah et al. http://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Internal Medicine
Nasrullah, Adeel
Fatima, Zainab
Javed, Anam
Tariq, Usman
Saleem, Muhammad Sabih
A Case of Anti-glomerular Basement Disease Without Pulmonary Involvement
title A Case of Anti-glomerular Basement Disease Without Pulmonary Involvement
title_full A Case of Anti-glomerular Basement Disease Without Pulmonary Involvement
title_fullStr A Case of Anti-glomerular Basement Disease Without Pulmonary Involvement
title_full_unstemmed A Case of Anti-glomerular Basement Disease Without Pulmonary Involvement
title_short A Case of Anti-glomerular Basement Disease Without Pulmonary Involvement
title_sort case of anti-glomerular basement disease without pulmonary involvement
topic Internal Medicine
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6485522/
https://www.ncbi.nlm.nih.gov/pubmed/31058013
http://dx.doi.org/10.7759/cureus.4130
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