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Thin Patient, Fatty Liver

A 49-year-old lady with no past medical history presented with dysphagia and 40-pound weight loss, which occurred over eight months. On physical examination, she had proximal muscle weakness and crackles in basilar regions of the lungs. Labs were significant for low albumin, elevated transaminases,...

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Autores principales: Mukthinuthalapati, V V Pavan Kedar, Attar, Bashar M, Abu Omar, Yazan, Nath, Vikas, Czapar, Carol, Gandhi, Seema R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6485526/
https://www.ncbi.nlm.nih.gov/pubmed/31058022
http://dx.doi.org/10.7759/cureus.4139
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author Mukthinuthalapati, V V Pavan Kedar
Attar, Bashar M
Abu Omar, Yazan
Nath, Vikas
Czapar, Carol
Gandhi, Seema R
author_facet Mukthinuthalapati, V V Pavan Kedar
Attar, Bashar M
Abu Omar, Yazan
Nath, Vikas
Czapar, Carol
Gandhi, Seema R
author_sort Mukthinuthalapati, V V Pavan Kedar
collection PubMed
description A 49-year-old lady with no past medical history presented with dysphagia and 40-pound weight loss, which occurred over eight months. On physical examination, she had proximal muscle weakness and crackles in basilar regions of the lungs. Labs were significant for low albumin, elevated transaminases, and high aldolase. Imaging suggested aspiration pneumonitis in both lungs and hepatic steatosis. A swallow evaluation revealed oropharyngeal dysphagia and muscle biopsy confirmed a rare form of myositis. A liver biopsy showed steatohepatitis and a diagnosis of starvation-induced steatohepatitis was made. The patient succumbed to hypoxic respiratory failure from aspiration pneumonitis before the treatment for myositis could be initiated. We report the first case of starvation-induced steatohepatitis in a patient with dysphagia from myositis affecting the oropharyngeal musculature.
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spelling pubmed-64855262019-05-03 Thin Patient, Fatty Liver Mukthinuthalapati, V V Pavan Kedar Attar, Bashar M Abu Omar, Yazan Nath, Vikas Czapar, Carol Gandhi, Seema R Cureus Internal Medicine A 49-year-old lady with no past medical history presented with dysphagia and 40-pound weight loss, which occurred over eight months. On physical examination, she had proximal muscle weakness and crackles in basilar regions of the lungs. Labs were significant for low albumin, elevated transaminases, and high aldolase. Imaging suggested aspiration pneumonitis in both lungs and hepatic steatosis. A swallow evaluation revealed oropharyngeal dysphagia and muscle biopsy confirmed a rare form of myositis. A liver biopsy showed steatohepatitis and a diagnosis of starvation-induced steatohepatitis was made. The patient succumbed to hypoxic respiratory failure from aspiration pneumonitis before the treatment for myositis could be initiated. We report the first case of starvation-induced steatohepatitis in a patient with dysphagia from myositis affecting the oropharyngeal musculature. Cureus 2019-02-26 /pmc/articles/PMC6485526/ /pubmed/31058022 http://dx.doi.org/10.7759/cureus.4139 Text en Copyright © 2019, Mukthinuthalapati et al. http://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Internal Medicine
Mukthinuthalapati, V V Pavan Kedar
Attar, Bashar M
Abu Omar, Yazan
Nath, Vikas
Czapar, Carol
Gandhi, Seema R
Thin Patient, Fatty Liver
title Thin Patient, Fatty Liver
title_full Thin Patient, Fatty Liver
title_fullStr Thin Patient, Fatty Liver
title_full_unstemmed Thin Patient, Fatty Liver
title_short Thin Patient, Fatty Liver
title_sort thin patient, fatty liver
topic Internal Medicine
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6485526/
https://www.ncbi.nlm.nih.gov/pubmed/31058022
http://dx.doi.org/10.7759/cureus.4139
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