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Thin Patient, Fatty Liver
A 49-year-old lady with no past medical history presented with dysphagia and 40-pound weight loss, which occurred over eight months. On physical examination, she had proximal muscle weakness and crackles in basilar regions of the lungs. Labs were significant for low albumin, elevated transaminases,...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cureus
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6485526/ https://www.ncbi.nlm.nih.gov/pubmed/31058022 http://dx.doi.org/10.7759/cureus.4139 |
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author | Mukthinuthalapati, V V Pavan Kedar Attar, Bashar M Abu Omar, Yazan Nath, Vikas Czapar, Carol Gandhi, Seema R |
author_facet | Mukthinuthalapati, V V Pavan Kedar Attar, Bashar M Abu Omar, Yazan Nath, Vikas Czapar, Carol Gandhi, Seema R |
author_sort | Mukthinuthalapati, V V Pavan Kedar |
collection | PubMed |
description | A 49-year-old lady with no past medical history presented with dysphagia and 40-pound weight loss, which occurred over eight months. On physical examination, she had proximal muscle weakness and crackles in basilar regions of the lungs. Labs were significant for low albumin, elevated transaminases, and high aldolase. Imaging suggested aspiration pneumonitis in both lungs and hepatic steatosis. A swallow evaluation revealed oropharyngeal dysphagia and muscle biopsy confirmed a rare form of myositis. A liver biopsy showed steatohepatitis and a diagnosis of starvation-induced steatohepatitis was made. The patient succumbed to hypoxic respiratory failure from aspiration pneumonitis before the treatment for myositis could be initiated. We report the first case of starvation-induced steatohepatitis in a patient with dysphagia from myositis affecting the oropharyngeal musculature. |
format | Online Article Text |
id | pubmed-6485526 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
publisher | Cureus |
record_format | MEDLINE/PubMed |
spelling | pubmed-64855262019-05-03 Thin Patient, Fatty Liver Mukthinuthalapati, V V Pavan Kedar Attar, Bashar M Abu Omar, Yazan Nath, Vikas Czapar, Carol Gandhi, Seema R Cureus Internal Medicine A 49-year-old lady with no past medical history presented with dysphagia and 40-pound weight loss, which occurred over eight months. On physical examination, she had proximal muscle weakness and crackles in basilar regions of the lungs. Labs were significant for low albumin, elevated transaminases, and high aldolase. Imaging suggested aspiration pneumonitis in both lungs and hepatic steatosis. A swallow evaluation revealed oropharyngeal dysphagia and muscle biopsy confirmed a rare form of myositis. A liver biopsy showed steatohepatitis and a diagnosis of starvation-induced steatohepatitis was made. The patient succumbed to hypoxic respiratory failure from aspiration pneumonitis before the treatment for myositis could be initiated. We report the first case of starvation-induced steatohepatitis in a patient with dysphagia from myositis affecting the oropharyngeal musculature. Cureus 2019-02-26 /pmc/articles/PMC6485526/ /pubmed/31058022 http://dx.doi.org/10.7759/cureus.4139 Text en Copyright © 2019, Mukthinuthalapati et al. http://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. |
spellingShingle | Internal Medicine Mukthinuthalapati, V V Pavan Kedar Attar, Bashar M Abu Omar, Yazan Nath, Vikas Czapar, Carol Gandhi, Seema R Thin Patient, Fatty Liver |
title | Thin Patient, Fatty Liver |
title_full | Thin Patient, Fatty Liver |
title_fullStr | Thin Patient, Fatty Liver |
title_full_unstemmed | Thin Patient, Fatty Liver |
title_short | Thin Patient, Fatty Liver |
title_sort | thin patient, fatty liver |
topic | Internal Medicine |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6485526/ https://www.ncbi.nlm.nih.gov/pubmed/31058022 http://dx.doi.org/10.7759/cureus.4139 |
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