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Vaccination with a chikungunya virus-like particle vaccine exacerbates disease in aged mice
INTRODUCTION: Chikungunya virus (CHIKV) is a re-emerging pathogen responsible for causing outbreaks of febrile disease accompanied with debilitating joint pain. Symptoms typically persist for two weeks, but more severe and chronic chikungunya illnesses have been reported, especially in the elderly....
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6485612/ https://www.ncbi.nlm.nih.gov/pubmed/31026260 http://dx.doi.org/10.1371/journal.pntd.0007316 |