Checkpoint Proteins Bub1 and Bub3 Delay Anaphase Onset in Response to Low Tension Independent of Microtubule-Kinetochore Detachment

The spindle assembly checkpoint (SAC) delays anaphase onset until sister chromosomes are bound to microtubules from opposite spindle poles. Only then can dynamic microtubules produce tension across sister kinetochores. The interdependence of kinetochore attachment and tension has proved challenging...

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Detalles Bibliográficos
Autores principales: Proudfoot, Kathleen G., Anderson, Samuel J., Dave, Sandeep, Bunning, Angela R., Roy, Pallavi Sinha, Bera, Abesh, Gupta, Mohan L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6485967/
https://www.ncbi.nlm.nih.gov/pubmed/30970246
http://dx.doi.org/10.1016/j.celrep.2019.03.027

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6485967/
https://www.ncbi.nlm.nih.gov/pubmed/30970246
http://dx.doi.org/10.1016/j.celrep.2019.03.027

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