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Optical fiber bundles: Ultra-slim light field imaging probes

Optical fiber bundle microendoscopes are widely used for visualizing hard-to-reach areas of the human body. These ultrathin devices often forgo tunable focusing optics because of size constraints and are therefore limited to two-dimensional (2D) imaging modalities. Ideally, microendoscopes would rec...

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Autores principales: Orth, A., Ploschner, M., Wilson, E. R., Maksymov, I. S., Gibson, B. C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6486219/
https://www.ncbi.nlm.nih.gov/pubmed/31032405
http://dx.doi.org/10.1126/sciadv.aav1555
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author Orth, A.
Ploschner, M.
Wilson, E. R.
Maksymov, I. S.
Gibson, B. C.
author_facet Orth, A.
Ploschner, M.
Wilson, E. R.
Maksymov, I. S.
Gibson, B. C.
author_sort Orth, A.
collection PubMed
description Optical fiber bundle microendoscopes are widely used for visualizing hard-to-reach areas of the human body. These ultrathin devices often forgo tunable focusing optics because of size constraints and are therefore limited to two-dimensional (2D) imaging modalities. Ideally, microendoscopes would record 3D information for accurate clinical and biological interpretation, without bulky optomechanical parts. Here, we demonstrate that the optical fiber bundles commonly used in microendoscopy are inherently sensitive to depth information. We use the mode structure within fiber bundle cores to extract the spatio-angular description of captured light rays—the light field—enabling digital refocusing, stereo visualization, and surface and depth mapping of microscopic scenes at the distal fiber tip. Our work opens a route for minimally invasive clinical microendoscopy using standard bare fiber bundle probes. Unlike coherent 3D multimode fiber imaging techniques, our incoherent approach is single shot and resilient to fiber bending, making it attractive for clinical adoption.
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spelling pubmed-64862192019-04-27 Optical fiber bundles: Ultra-slim light field imaging probes Orth, A. Ploschner, M. Wilson, E. R. Maksymov, I. S. Gibson, B. C. Sci Adv Research Articles Optical fiber bundle microendoscopes are widely used for visualizing hard-to-reach areas of the human body. These ultrathin devices often forgo tunable focusing optics because of size constraints and are therefore limited to two-dimensional (2D) imaging modalities. Ideally, microendoscopes would record 3D information for accurate clinical and biological interpretation, without bulky optomechanical parts. Here, we demonstrate that the optical fiber bundles commonly used in microendoscopy are inherently sensitive to depth information. We use the mode structure within fiber bundle cores to extract the spatio-angular description of captured light rays—the light field—enabling digital refocusing, stereo visualization, and surface and depth mapping of microscopic scenes at the distal fiber tip. Our work opens a route for minimally invasive clinical microendoscopy using standard bare fiber bundle probes. Unlike coherent 3D multimode fiber imaging techniques, our incoherent approach is single shot and resilient to fiber bending, making it attractive for clinical adoption. American Association for the Advancement of Science 2019-04-26 /pmc/articles/PMC6486219/ /pubmed/31032405 http://dx.doi.org/10.1126/sciadv.aav1555 Text en Copyright © 2019 The Authors, some rights reserved; exclusive licensee American Association for the Advancement of Science. No claim to original U.S. Government Works. Distributed under a Creative Commons Attribution NonCommercial License 4.0 (CC BY-NC). http://creativecommons.org/licenses/by-nc/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial license (http://creativecommons.org/licenses/by-nc/4.0/) , which permits use, distribution, and reproduction in any medium, so long as the resultant use is not for commercial advantage and provided the original work is properly cited.
spellingShingle Research Articles
Orth, A.
Ploschner, M.
Wilson, E. R.
Maksymov, I. S.
Gibson, B. C.
Optical fiber bundles: Ultra-slim light field imaging probes
title Optical fiber bundles: Ultra-slim light field imaging probes
title_full Optical fiber bundles: Ultra-slim light field imaging probes
title_fullStr Optical fiber bundles: Ultra-slim light field imaging probes
title_full_unstemmed Optical fiber bundles: Ultra-slim light field imaging probes
title_short Optical fiber bundles: Ultra-slim light field imaging probes
title_sort optical fiber bundles: ultra-slim light field imaging probes
topic Research Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6486219/
https://www.ncbi.nlm.nih.gov/pubmed/31032405
http://dx.doi.org/10.1126/sciadv.aav1555
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