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BTK SIGNALING DRIVES CD1d(hi)CD5(+) REGULATORY B CELL DIFFERENTIATION TO PROMOTE PANCREATIC CARCINOGENESIS

The immune microenvironment of pancreatic ductal adenocarcinoma (PDAC) is comprised of a heterogeneous population of cells that are critical for disease evolution. Prominent among these are the specialized CD1d(hi)CD5(+) regulatory B (B(reg)) cells that exert a pro-tumorigenic role by promoting tumo...

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Detalles Bibliográficos
Autores principales:	Das, Shipra, Bar-Sagi, Dafna
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6486434/ https://www.ncbi.nlm.nih.gov/pubmed/30635655 http://dx.doi.org/10.1038/s41388-018-0668-3

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