PAD2-Mediated Citrullination Contributes to Efficient Oligodendrocyte Differentiation and Myelination

Citrullination, the deimination of peptidylarginine residues into peptidylcitrulline, has been implicated in the etiology of several diseases. In multiple sclerosis, citrullination is thought to be a major driver of pathology through hypercitrullination and destabilization of myelin. As such, inhibi...

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Detalles Bibliográficos
Autores principales: Falcão, Ana Mendanha, Meijer, Mandy, Scaglione, Antonella, Rinwa, Puneet, Agirre, Eneritz, Liang, Jialiang, Larsen, Sara C., Heskol, Abeer, Frawley, Rebecca, Klingener, Michael, Varas-Godoy, Manuel, Raposo, Alexandre A.S.F., Ernfors, Patrik, Castro, Diogo S., Nielsen, Michael L., Casaccia, Patrizia, Castelo-Branco, Gonçalo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6486480/
https://www.ncbi.nlm.nih.gov/pubmed/31018126
http://dx.doi.org/10.1016/j.celrep.2019.03.108

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