YAP Activity Is Necessary and Sufficient for Basal Progenitor Abundance and Proliferation in the Developing Neocortex

Neocortex expansion during mammalian evolution has been linked to an increase in proliferation of basal progenitors in the subventricular zone. Here, we explored a potential role of YAP, the major downstream effector of the Hippo pathway, in proliferation of basal progenitors. YAP expression and act...

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Detalles Bibliográficos
Autores principales: Kostic, Milos, Paridaen, Judith T.M.L., Long, Katherine R., Kalebic, Nereo, Langen, Barbara, Grübling, Nannette, Wimberger, Pauline, Kawasaki, Hiroshi, Namba, Takashi, Huttner, Wieland B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6486488/
https://www.ncbi.nlm.nih.gov/pubmed/31018127
http://dx.doi.org/10.1016/j.celrep.2019.03.091

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