Cargando…

Studies on wound healing potential of red pigment isolated from marine Bacterium Vibrio sp.

Wounds are common clinical entities of life which may be subacute or acute. Wound healing is a complex biochemical process where the cell structures are restored to normalcy, which depend on cell proliferation and migration, basically fibroblast cell. The present investigation was undertaken to eval...

Descripción completa

Detalles Bibliográficos
Autores principales: Shiva Krishna, Pabba, Sudha, S., Reddy, K. Ashok, Al-Dhabaan, Fahad A., Meher, Prakasham, R.S., Singara Charya, M.A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6486536/
https://www.ncbi.nlm.nih.gov/pubmed/31048996
http://dx.doi.org/10.1016/j.sjbs.2017.11.035
_version_ 1783414355664044032
author Shiva Krishna, Pabba
Sudha, S.
Reddy, K. Ashok
Al-Dhabaan, Fahad A.
Meher
Prakasham, R.S.
Singara Charya, M.A.
author_facet Shiva Krishna, Pabba
Sudha, S.
Reddy, K. Ashok
Al-Dhabaan, Fahad A.
Meher
Prakasham, R.S.
Singara Charya, M.A.
author_sort Shiva Krishna, Pabba
collection PubMed
description Wounds are common clinical entities of life which may be subacute or acute. Wound healing is a complex biochemical process where the cell structures are restored to normalcy, which depend on cell proliferation and migration, basically fibroblast cell. The present investigation was undertaken to evaluate the healing efficacy of red pigment isolated from marine isolate Vibrio sps on experimental wounds in albino rats. The red pigment was applied topically, twice daily for 14 days. Treatment with framycetin ointment was used as reference control. The red pigment treated group showed faster reduction in wound area in comparison with control and framycetin ointment treated groups. In conclusion, red pigment possesses significant healing potential in wounds and has a positive influence on the different phases of wound repair.
format Online
Article
Text
id pubmed-6486536
institution National Center for Biotechnology Information
language English
publishDate 2019
publisher Elsevier
record_format MEDLINE/PubMed
spelling pubmed-64865362019-05-02 Studies on wound healing potential of red pigment isolated from marine Bacterium Vibrio sp. Shiva Krishna, Pabba Sudha, S. Reddy, K. Ashok Al-Dhabaan, Fahad A. Meher Prakasham, R.S. Singara Charya, M.A. Saudi J Biol Sci Article Wounds are common clinical entities of life which may be subacute or acute. Wound healing is a complex biochemical process where the cell structures are restored to normalcy, which depend on cell proliferation and migration, basically fibroblast cell. The present investigation was undertaken to evaluate the healing efficacy of red pigment isolated from marine isolate Vibrio sps on experimental wounds in albino rats. The red pigment was applied topically, twice daily for 14 days. Treatment with framycetin ointment was used as reference control. The red pigment treated group showed faster reduction in wound area in comparison with control and framycetin ointment treated groups. In conclusion, red pigment possesses significant healing potential in wounds and has a positive influence on the different phases of wound repair. Elsevier 2019-05 2017-11-15 /pmc/articles/PMC6486536/ /pubmed/31048996 http://dx.doi.org/10.1016/j.sjbs.2017.11.035 Text en © 2017 The Authors. Production and hosting by Elsevier B.V. on behalf of King Saud University. http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Article
Shiva Krishna, Pabba
Sudha, S.
Reddy, K. Ashok
Al-Dhabaan, Fahad A.
Meher
Prakasham, R.S.
Singara Charya, M.A.
Studies on wound healing potential of red pigment isolated from marine Bacterium Vibrio sp.
title Studies on wound healing potential of red pigment isolated from marine Bacterium Vibrio sp.
title_full Studies on wound healing potential of red pigment isolated from marine Bacterium Vibrio sp.
title_fullStr Studies on wound healing potential of red pigment isolated from marine Bacterium Vibrio sp.
title_full_unstemmed Studies on wound healing potential of red pigment isolated from marine Bacterium Vibrio sp.
title_short Studies on wound healing potential of red pigment isolated from marine Bacterium Vibrio sp.
title_sort studies on wound healing potential of red pigment isolated from marine bacterium vibrio sp.
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6486536/
https://www.ncbi.nlm.nih.gov/pubmed/31048996
http://dx.doi.org/10.1016/j.sjbs.2017.11.035
work_keys_str_mv AT shivakrishnapabba studiesonwoundhealingpotentialofredpigmentisolatedfrommarinebacteriumvibriosp
AT sudhas studiesonwoundhealingpotentialofredpigmentisolatedfrommarinebacteriumvibriosp
AT reddykashok studiesonwoundhealingpotentialofredpigmentisolatedfrommarinebacteriumvibriosp
AT aldhabaanfahada studiesonwoundhealingpotentialofredpigmentisolatedfrommarinebacteriumvibriosp
AT meher studiesonwoundhealingpotentialofredpigmentisolatedfrommarinebacteriumvibriosp
AT prakashamrs studiesonwoundhealingpotentialofredpigmentisolatedfrommarinebacteriumvibriosp
AT singaracharyama studiesonwoundhealingpotentialofredpigmentisolatedfrommarinebacteriumvibriosp