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Studies on wound healing potential of red pigment isolated from marine Bacterium Vibrio sp.
Wounds are common clinical entities of life which may be subacute or acute. Wound healing is a complex biochemical process where the cell structures are restored to normalcy, which depend on cell proliferation and migration, basically fibroblast cell. The present investigation was undertaken to eval...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6486536/ https://www.ncbi.nlm.nih.gov/pubmed/31048996 http://dx.doi.org/10.1016/j.sjbs.2017.11.035 |
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author | Shiva Krishna, Pabba Sudha, S. Reddy, K. Ashok Al-Dhabaan, Fahad A. Meher Prakasham, R.S. Singara Charya, M.A. |
author_facet | Shiva Krishna, Pabba Sudha, S. Reddy, K. Ashok Al-Dhabaan, Fahad A. Meher Prakasham, R.S. Singara Charya, M.A. |
author_sort | Shiva Krishna, Pabba |
collection | PubMed |
description | Wounds are common clinical entities of life which may be subacute or acute. Wound healing is a complex biochemical process where the cell structures are restored to normalcy, which depend on cell proliferation and migration, basically fibroblast cell. The present investigation was undertaken to evaluate the healing efficacy of red pigment isolated from marine isolate Vibrio sps on experimental wounds in albino rats. The red pigment was applied topically, twice daily for 14 days. Treatment with framycetin ointment was used as reference control. The red pigment treated group showed faster reduction in wound area in comparison with control and framycetin ointment treated groups. In conclusion, red pigment possesses significant healing potential in wounds and has a positive influence on the different phases of wound repair. |
format | Online Article Text |
id | pubmed-6486536 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
publisher | Elsevier |
record_format | MEDLINE/PubMed |
spelling | pubmed-64865362019-05-02 Studies on wound healing potential of red pigment isolated from marine Bacterium Vibrio sp. Shiva Krishna, Pabba Sudha, S. Reddy, K. Ashok Al-Dhabaan, Fahad A. Meher Prakasham, R.S. Singara Charya, M.A. Saudi J Biol Sci Article Wounds are common clinical entities of life which may be subacute or acute. Wound healing is a complex biochemical process where the cell structures are restored to normalcy, which depend on cell proliferation and migration, basically fibroblast cell. The present investigation was undertaken to evaluate the healing efficacy of red pigment isolated from marine isolate Vibrio sps on experimental wounds in albino rats. The red pigment was applied topically, twice daily for 14 days. Treatment with framycetin ointment was used as reference control. The red pigment treated group showed faster reduction in wound area in comparison with control and framycetin ointment treated groups. In conclusion, red pigment possesses significant healing potential in wounds and has a positive influence on the different phases of wound repair. Elsevier 2019-05 2017-11-15 /pmc/articles/PMC6486536/ /pubmed/31048996 http://dx.doi.org/10.1016/j.sjbs.2017.11.035 Text en © 2017 The Authors. Production and hosting by Elsevier B.V. on behalf of King Saud University. http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/). |
spellingShingle | Article Shiva Krishna, Pabba Sudha, S. Reddy, K. Ashok Al-Dhabaan, Fahad A. Meher Prakasham, R.S. Singara Charya, M.A. Studies on wound healing potential of red pigment isolated from marine Bacterium Vibrio sp. |
title | Studies on wound healing potential of red pigment isolated from marine Bacterium Vibrio sp. |
title_full | Studies on wound healing potential of red pigment isolated from marine Bacterium Vibrio sp. |
title_fullStr | Studies on wound healing potential of red pigment isolated from marine Bacterium Vibrio sp. |
title_full_unstemmed | Studies on wound healing potential of red pigment isolated from marine Bacterium Vibrio sp. |
title_short | Studies on wound healing potential of red pigment isolated from marine Bacterium Vibrio sp. |
title_sort | studies on wound healing potential of red pigment isolated from marine bacterium vibrio sp. |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6486536/ https://www.ncbi.nlm.nih.gov/pubmed/31048996 http://dx.doi.org/10.1016/j.sjbs.2017.11.035 |
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