Poly(ADP-ribosyl)ation by PARP1: reaction mechanism and regulatory proteins

Poly(ADP-ribosyl)ation (PARylation) is posttranslational modification of proteins by linear or branched chains of ADP-ribose units, originating from NAD+. The central enzyme for PAR production in cells and the main target of poly(ADP-ribosyl)ation during DNA damage is poly(ADP-ribose) polymerase 1 (...

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Detalles Bibliográficos
Autores principales: Alemasova, Elizaveta E, Lavrik, Olga I
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Survey and Summary
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6486540/
https://www.ncbi.nlm.nih.gov/pubmed/30799503
http://dx.doi.org/10.1093/nar/gkz120

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6486540/
https://www.ncbi.nlm.nih.gov/pubmed/30799503
http://dx.doi.org/10.1093/nar/gkz120

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