Cargando…
Poly(ADP-ribosyl)ation by PARP1: reaction mechanism and regulatory proteins
Poly(ADP-ribosyl)ation (PARylation) is posttranslational modification of proteins by linear or branched chains of ADP-ribose units, originating from NAD+. The central enzyme for PAR production in cells and the main target of poly(ADP-ribosyl)ation during DNA damage is poly(ADP-ribose) polymerase 1 (...
Autores principales: | Alemasova, Elizaveta E, Lavrik, Olga I |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6486540/ https://www.ncbi.nlm.nih.gov/pubmed/30799503 http://dx.doi.org/10.1093/nar/gkz120 |
Ejemplares similares
-
Poly(ADP-ribosyl)ation in mammalian ageing
por: Beneke, Sascha, et al.
Publicado: (2007) -
The role of poly ADP-ribosylation in the first wave of DNA damage response
por: Liu, Chao, et al.
Publicado: (2017) -
Mass spectrometry for serine ADP-ribosylation? Think o-glycosylation!
por: Bonfiglio, Juan J., et al.
Publicado: (2017) -
The contribution of PARP1, PARP2 and poly(ADP-ribosyl)ation to base excision repair in the nucleosomal context
por: Kutuzov, M. M., et al.
Publicado: (2021) -
ADP-ribosylation of RNA and DNA: from in vitro characterization to in vivo function
por: Weixler, Lisa, et al.
Publicado: (2021)