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En bloc and segmental deletions of human XIST reveal X chromosome inactivation-involving RNA elements

The XIST RNA is a non-coding RNA that induces X chromosome inactivation (XCI). Unlike the mouse Xist RNA, how the human XIST RNA controls XCI in female cells is less well characterized, and its functional motifs remain unclear. To systematically decipher the XCI-involving elements of XIST RNA, 11 sm...

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Detalles Bibliográficos
Autores principales: Lee, Hyeon J, Gopalappa, Ramu, Sunwoo, Hongjae, Choi, Seo-Won, Ramakrishna, Suresh, Lee, Jeannie T, Kim, Hyongbum H, Nam, Jin-Wu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6486550/
https://www.ncbi.nlm.nih.gov/pubmed/30783652
http://dx.doi.org/10.1093/nar/gkz109

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