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En bloc and segmental deletions of human XIST reveal X chromosome inactivation-involving RNA elements
The XIST RNA is a non-coding RNA that induces X chromosome inactivation (XCI). Unlike the mouse Xist RNA, how the human XIST RNA controls XCI in female cells is less well characterized, and its functional motifs remain unclear. To systematically decipher the XCI-involving elements of XIST RNA, 11 sm...
Autores principales: | Lee, Hyeon J, Gopalappa, Ramu, Sunwoo, Hongjae, Choi, Seo-Won, Ramakrishna, Suresh, Lee, Jeannie T, Kim, Hyongbum H, Nam, Jin-Wu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6486550/ https://www.ncbi.nlm.nih.gov/pubmed/30783652 http://dx.doi.org/10.1093/nar/gkz109 |
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